Protein Alignment Glut3 and HXT8

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_012321.1
• Gene: HXT8 / 853216
• SGDID: S000003750
• Length: 569
• Species: Saccharomyces cerevisiae
• Alignment Length: 537
• Identity: 121/537 - (22%)
• Similarity: 211/537 - (39%)
• Gaps: 133/537 - (24%)

  Fly    30 SEMPERHVERAPVRQKINNVGLYKATLYSNIGSF-----FFGIAVGW-SGTAERSVME------- 81
            ||......|...|.:|       .|:.|:.:...     |.|...|| :||....|.:
Yeast    43 SEYNGEEAEEVVVPEK-------PASAYATVSIMCLCMAFGGFMSGWDTGTISGFVNQTDFLRRF 100

  Fly    82 -QHSYS---FQPTELQWSGVCILLTLGAALWCL-----------PMGLMVRLLGCRRTILIQLLP 131
             .:|:|   :..:.::...:..:..:|:|:.||           .|||::.::.....|:|| :.
Yeast   101 GNYSHSKNTYYLSNVRTGLIVSIFNVGSAIGCLFLSKLGDIYGRCMGLIIVIVVYMVGIVIQ-IA 164

  Fly   132 NFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAM---------GVVFE 187
            :...|:         ..:.||...|:..|:..|:.|:..:|.:....||.:         ..:|.
Yeast   165 SIDKWY---------QYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTLLACWQLMVTFAIFL 220

  Fly   188 GACICGVIYSFAMSLFLELRIINFVNLGL------LALGPLQILMPESPAYYVDHGNIPRAEDSL 246
            |.|......:::.|  ::.|    |.|||      :.:|.: ..:||||.:.|..|.|.:|:.|
Yeast   221 GYCTNYGTKTYSNS--VQWR----VPLGLCFAWAIIMIGGM-TFVPESPRFLVQVGKIEQAKAS- 277

  Fly   247 RFLRGQKYDTR-----REIDFLTRD-------PTESEREVRQGPLLGFKYK-KVRRSLARSLAIA 298
             |.:..|....     .|||.|...       .|.|.:|:       |..| ||.:.|..::.|.
Yeast   278 -FAKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKEL-------FSRKTKVFQRLTMTVMIN 334

  Fly   299 LLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACFF---LVDRLGRRPLLIFSSAG 360
            .||:|.|...|.:||..:...:.:...|...:.|| |:.|.:|||   .||:||||..|:..:|.
Yeast   335 SLQQLTGDNYFFYYGTTIFKSVGMNDSFETSIVLG-IVNFASCFFSLYSVDKLGRRRCLLLGAAT 398

  Fly   361 IVFVSIYLGLHFKVWMTMGLTVM---------------SWIALFCIAIFVGCYTAGVGSLTWVLN 410
            :....:       ::.::|:|.:               ..|...|..||  |::...|.:.:|:.
Yeast   399 MTACMV-------IYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIF--CFSCTWGPVCYVII 454

  Fly   411 AELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLF----LLFAIIASLILLFSLIY- 470
            :|.....:|....|:..|.|.|.. |:|.:|       .|::.    ..:..:....|.||..|
Yeast   455 SETFPLRVRSKCMSVATAANLLWG-FLIGFF-------TPFITSAINFYYGYVFMGCLAFSYFYV 511

  Fly   471 ---IPETKKLSSAKIQQ 484
               :||||.|:..::.:
Yeast   512 FFFVPETKGLTLEEVDE 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	115/507 (23%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	114/504 (23%)