Protein Alignment Glut3 and VPS73

DIOPT Version :9

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 512
• Identity: 116/512 - (22%)
• Similarity: 214/512 - (41%)
• Gaps: 110/512 - (21%)

  Fly    32 MPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSF----QPTEL 92
            ||.::      :.||.....| |.:.::|||..||..:. ...|.:.|:....:..    .|.:.
Yeast    16 MPRQN------KHKITKALCY-AIIVASIGSIQFGYHLS-ELNAPQQVLSCSEFDIPMEGYPYDR 72

  Fly    93 QWSG-----VCILLT-----LGAALWCLPMGL--------MVRLLGCRRTILIQLLPNFLGWFLT 139
            .|.|     .||.|.     :..:::|:. |:        :..:.|.:.:.||....|.:|..:.
Yeast    73 TWLGKRGYKQCIPLNDEQIGIVTSVFCIG-GILGSYFATSLANIYGRKFSSLINCTLNIVGSLII 136

  Fly   140 VFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSL-- 202
            ..:.|...|..||..:|:..|:..|::|::..|::.:...|.:|.:.:.....||:.:..::|
Yeast   137 FNSNSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPL 201

  Fly   203 -------------FLELRIINFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKY 254
                         || :.::||.         :..::.|||.:.:.||.:..|:.||..|||..:
Yeast   202 TDSYRWRWILFGSFL-IAVLNFF---------MWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTF 256

  Fly   255 D-TRREIDFLTRDPTESEREVRQG-PLLG-------------FKYKKVRRSLARSLAIALL---Q 301
            | ..:||.       :.:.::..| ||:.             :||.:.|.::.....|.:|   |
Yeast   257 DEAAQEIQ-------DWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQ 314

  Fly   302 KLCGALIFIFYGLNMLD------CLRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAG 360
            :.||....:.||..::.      .:||.....::..|..||..|    |:..|.|:|||:.|:..
Yeast   315 QFCGINSIVLYGTKIISQLYPQHAIRINFFISMVNVLVTILVSL----LIHSLPRKPLLMTSTVL 375

  Fly   361 IVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAEL-----LVRPMRP 420
            :...:..:|:      .|....|:.:.:|.. |::|.:|.|:..|.:::..|:     :|...|
Yeast   376 VSVTAFIMGI------AMNHNKMNLLIVFSF-IYMGVFTMGLNPLPFIIMREVSKPQDMVLAQR- 432

  Fly   421 LGCSIVCAFNWLTAFFVICWFG-SHGVKCQPYLFLLFAIIASLILLFSLIYIPETKK 476
              ...:|  ||:..|.:...|. .|.| ...|:|::|||||..|..|....:||||:
Yeast   433 --YGTIC--NWVGTFIIAYTFPIIHDV-LSGYVFIIFAIIACSISAFIWKKVPETKR 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	110/484 (23%)
		MFS	63..>226	CDD:119392	35/199 (18%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	110/488 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342342
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840