Protein Alignment Glut3 and CIN10

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_010675.3
• Gene: CIN10 / 851995
• SGDID: S000002795
• Length: 555
• Species: Saccharomyces cerevisiae
• Alignment Length: 547
• Identity: 117/547 - (21%)
• Similarity: 190/547 - (34%)
• Gaps: 162/547 - (29%)

  Fly    52 YKATLY---SNIGSFFFGIAVGWSGTAERSVMEQHSYSFQP--------TELQWSGVCILLTLGA 105
            :|.:|.   :.||...||...|        |:.....|.:|        |::|...:....::|:
Yeast    37 FKTSLIFVGATIGGLLFGYDTG--------VISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGS 93

  Fly   106 ---ALWCLPM----GLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHC 163
               ::...|:    |..:.|..|....::..:.       ...||::..|..||..:|:..|...
Yeast    94 FFGSILAFPLADRYGRRITLAICCSIFILAAIG-------MAIARTLTFLICGRLLVGIAVGVSA 151

  Fly   164 VVVPIYNAEISTTKKRGAM-----GVVFEGACICGVI------------YSFAMS---LFLELRI 208
            ..||::.:|||.::.||.|     ..:..|..:..||            |.||:|   ..|.|.|
Yeast   152 QCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSI 216

  Fly   209 INFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRR-------------EI 260
            ::|:              ||||.:.:..|:|....||||.|    |.|..             |:
Yeast   217 LDFI--------------PESPRWSISKGDILYTRDSLRML----YPTASTYHVNSKIKQLIIEL 263

  Fly   261 DFL-----TRDP--TESEREVR------------------------------------------- 275
            |.|     ..:|  .:|:..:|
Yeast   264 DKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMSSSSAYLSALRGPA 328

  Fly   276 -QGPLLGFKYKKVR------RSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREF---GLIL 330
             .|.|...|.|:.|      |:|.....:...|::.|...|::|...:.....|:...   .||.
Yeast   329 PNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKFNIKNPLLPPILIA 393

  Fly   331 CLGLILGFLACFFLVDRLGRRPLL----IFSSAGIVFVSIYLGLHFKVWMTMGLTVMSWIALFCI 391
            ....|..|.| .:.:|.||||.:|    :..:.|::..|:..| |.:|          .:.|..:
Yeast   394 STNFIFTFFA-MYTMDSLGRRAILLRTILIMTVGLLLCSVGFG-HDQV----------NLLLISV 446

  Fly   392 AIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLT-AFFVICWFGSHGVKCQPYLFLL 455
            .|:|..|.:.:||:.|.. .|.|....|..|.|.:...|||| ||..:.:..:..........|:
Yeast   447 VIYVAAYASAMGSVPWTC-VEFLPLNRRSFGASCIACTNWLTNAFVSMTYLSTINTIGDENTMLI 510

  Fly   456 FAIIASLILLFSLIYIPETKKLSSAKI 482
            ||........|...:.||.|.||..::
Yeast   511 FAFFTVCAWFFVYFWYPEVKGLSLEEV 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	115/541 (21%)
CIN10	NP_010675.3	MFS_HMIT_like	45..528	CDD:340918	110/528 (21%)