Protein Alignment Glut3 and HXT6

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_010630.1
• Gene: HXT6 / 851944
• SGDID: S000002751
• Length: 570
• Species: Saccharomyces cerevisiae
• Alignment Length: 561
• Identity: 111/561 - (19%)
• Similarity: 210/561 - (37%)
• Gaps: 127/561 - (22%)

  Fly     6 IQDAEPVEPPQSSRKSGTWFAKRPSEMPERHVERA----PVRQKINNVGLYKATLYSNIGSF--- 63
            |.:..|||...:...:.......||...||...:|    ...:.:..:....|:.|..:...
Yeast     7 IAEQTPVEHLSAVDSASHSVLSTPSNKAERDEIKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIM 71

  Fly    64 --FFGIAVGW-SGT----------AERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLM 115
              |.|...|| :||          ..|..|:....:...::::...:..:..:|.|:..:.:..:
Yeast    72 IAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKL 136

  Fly   116 VRLLGCRRTILIQLLPNFLG----------WFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYN 170
            ..:.|.:..:::.::...:|          |:         ..:.||...|:..|...|:.|:..
Yeast   137 GDMYGRKVGLIVVVVIYIIGIIIQIASINKWY---------QYFIGRIISGLGVGGIAVLSPMLI 192

  Fly   171 AEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVN-------LGLLALGPLQIL--- 225
            :|:|....||.:...::.....|:...:..:...:    |:.|       |||.....|.::
Yeast   193 SEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTK----NYSNSVQWRVPLGLCFAWALFMIGGM 253

  Fly   226 --MPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPT------------ESER---E 273
              :||||.|..:.|.|..|:.|:........|          ||:            |:|:   .
Yeast   254 TFVPESPRYLAEVGKIEEAKRSIAVSNKVAVD----------DPSVLAEVEAVLAGVEAEKLAGN 308

  Fly   274 VRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLILGF 338
            ...|.|...|.|.::| |.....|..||:|.|...|.:||..:...:.:...|...:.|| |:.|
Yeast   309 ASWGELFSSKTKVLQR-LIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLSDSFETSIVLG-IVNF 371

  Fly   339 LACF---FLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSW--------------- 385
            .:.|   ::|:|.|||..|::.:|.:....:       |:.::|:|.: |
Yeast   372 ASTFVGIYVVERYGRRTCLLWGAASMTACMV-------VYASVGVTRL-WPNGQDQPSSKGAGNC 428

  Fly   386 -IALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQ 449
             |...|..||  |:......:.:|:.:|.....::....||..|.|||.. |:|.:|       .
Yeast   429 MIVFACFYIF--CFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWG-FLIGFF-------T 483

  Fly   450 PYL------FLLFAIIASLILLF--SLIYIPETKKLSSAKI 482
            |::      :..:..:..|:.:|  .|:.:||||.|:..::
Yeast   484 PFITGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTLEEV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	101/505 (20%)
HXT6	NP_010630.1	Sugar_tr	68..528	CDD:395036	100/500 (20%)