Protein Alignment Glut3 and MPH2

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_010034.1
• Gene: MPH2 / 851350
• SGDID: S000002406
• Length: 609
• Species: Saccharomyces cerevisiae
• Alignment Length: 453
• Identity: 104/453 - (22%)
• Similarity: 166/453 - (36%)
• Gaps: 95/453 - (20%)

  Fly    94 WS-GVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLG--WFLTVFARSVPMLYAGRFFL 155
            |. |:.:....|..:.....|..|.|:|.|.|::|.|.  ||.  .|:..|..|:.|:..|:...
Yeast   147 WQIGLTLCYMAGEIVGLQLTGPSVDLVGNRYTLIIALF--FLAAFTFILYFCNSLGMIAVGQALC 209

  Fly   156 GMCGGA-HCVVVPIYNAEISTTKKRGAMGVVFEGAC-ICGVIYS--------------------- 197
            ||..|. .|:.|. |.:||.....|..: ..:...| :.|.:::
Yeast   210 GMPWGCFQCLTVS-YASEICPLALRYYL-TTYSNLCWLFGQLFAAGIMKNSQKKYADSELGYKLP 272

  Fly   198 FAMSLFLELRIINFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRR---- 258
            ||:...|.:.         ||||  ....||||.:.|..|....|..|||.....|...:.
Yeast   273 FALQWILPVP---------LALG--IFFAPESPWWLVKKGRFDEARRSLRRTLSGKGPEKEILVT 326

  Fly   259 -EIDFL--TRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALL-QKLCGALIFIFYGLNMLDC 319
             |:|.:  |.| .|.....::|........|:.|...|...:... |..||: |.|.|.....:.
Yeast   327 LEVDKIKVTID-KEKRLTSKEGSYSDCFEDKINRRRTRITCLCWAGQATCGS-ILIGYSTYFYEK 389

  Fly   320 LRIRRE----FGLI-LCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYL----GLHFKVW 375
            ..:..|    |.:| .|||:...||: ::.....||..|..|   |:.|.:|..    ||...
Yeast   390 AGVSTEMSFTFSIIQYCLGICATFLS-WWASKYFGRYDLYAF---GLAFQTIVFFIIGGLGCS-- 448

  Fly   376 MTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVIC- 439
            .|.|..:.|...|..:|.|   |..|:..:.:.|.:|:....:|..  :|:.|.|......:||
Yeast   449 STHGSKMGSGSLLMAVAFF---YNLGIAPVVFCLVSEMPSSRLRTK--TIILARNTYNVVSIICS 508

  Fly   440 -------------WFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQ--RLG 487
                         |....|        ..:.::....|:::::.:|||...:..:|.:  :||
Yeast   509 VLILYQLNSKKWNWGAKSG--------FFWGVLCFCTLIWAVVDLPETAGKTFVEINELFKLG 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	101/440 (23%)
MPH2	NP_010034.1	SP	72..556	CDD:273317	101/444 (23%)