DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and ERDL6

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_177658.1	Gene:	ERDL6 / 843859	AraportID:	AT1G75220	Length:	487	Species:	Arabidopsis thaliana

Alignment Length:	485	Identity:	119/485 - (24%)
Similarity:	220/485 - (45%)	Gaps:	44/485 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SGTWF---AKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQ 82
            :|:|:   :::.|.|....|.|.      :::.:....|...:|...||...|:|...:.::.:.
plant    21 TGSWYRMGSRQSSMMGSSQVIRD------SSISVLACVLIVALGPIQFGFTCGYSSPTQAAITKD 79

  Fly    83 HSYSFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPM 147
            ...    |..::|....|..:||.:..:..|.:...:|.:.:::|..:||.:||....||:....
plant    80 LGL----TVSEYSVFGSLSNVGAMVGAIASGQIAEYIGRKGSLMIAAIPNIIGWLCISFAKDTSF 140

  Fly   148 LYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFV 212
            ||.||...|...|.....||:|.|||:....||.:|.|.:.:...|::.::.:.||:..||:  .
plant   141 LYMGRLLEGFGVGIISYTVPVYIAEIAPQNMRGGLGSVNQLSVTIGIMLAYLLGLFVPWRIL--A 203

  Fly   213 NLGLL---ALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESERE- 273
            .||:|   .|.|....:||||.:....|.....|.||:.|||.:.|...|::.:.|....|.:.
plant   204 VLGILPCTLLIPGLFFIPESPRWLAKMGMTDEFETSLQVLRGFETDITVEVNEIKRSVASSTKRN 268

  Fly   274 -VRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLI-- 335
             ||   .:..|.::....|...:.:.:||:|.|....:||...:.:...:.........:|.|
plant   269 TVR---FVDLKRRRYYFPLMVGIGLLVLQQLGGINGVLFYSSTIFESAGVTSSNAATFGVGAIQV 330

  Fly   336 LGFLACFFLVDRLGRRPLLIFSSAG--IVFVSIYLGLHFKVWMTMGLTVMSWIALFC---IAIFV 395
            :......:|||:.|||.||..||.|  |..|.:....:.|.:::....:.||:::..   :...|
plant   331 VATAISTWLVDKAGRRLLLTISSVGMTISLVIVAAAFYLKEFVSPDSDMYSWLSILSVVGVVAMV 395

  Fly   396 GCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNW-------LTAFFVICWFGSHGVKCQPYLF 453
            ..::.|:|.:.|::.:|:|...::.|..||....||       :||..::.| .|.|.      |
plant   396 VFFSLGMGPIPWLIMSEILPVNIKGLAGSIATLANWFFSWLITMTANLLLAW-SSGGT------F 453

  Fly   454 LLFAIIASLILLFSLIYIPETKKLSSAKIQ 483
            .|:.::.:..::|..:::||||..:..::|
plant   454 TLYGLVCAFTVVFVTLWVPETKGKTLEELQ 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	112/443 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	44/165 (27%)
ERDL6	NP_177658.1	MFS_GLUT6_8_Class3_like	49..481	CDD:340916	112/447 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920