DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and AT5G18840

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_568367.1	Gene:	AT5G18840 / 832002	AraportID:	AT5G18840	Length:	482	Species:	Arabidopsis thaliana

Alignment Length:	504	Identity:	125/504 - (24%)
Similarity:	211/504 - (41%)	Gaps:	90/504 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 RHVERAPVRQKINNVG-----------------LYKATLYSNI----GSFFFGIAVGWSGTAERS 78
            :.|||..:..|:.::|                 .|...|:|..    |||.||..||:|...:.|
plant     7 KDVERGEIVNKVEDLGKPFLTHEDDEKESENNESYLMVLFSTFVAVCGSFEFGSCVGYSAPTQSS 71

  Fly    79 VMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFAR 143
            :.:..:.|.    .::|....:||:||.|..:..|.:....|.:..:.........||....|.:
plant    72 IRQDLNLSL----AEFSMFGSILTIGAMLGAVMSGKISDFSGRKGAMRTSACFCITGWLAVFFTK 132

  Fly   144 SVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRI 208
            ...:|..||||.|...|....|||:|.||||....||.:..:.:...:.|...||.:.     .:
plant   133 GALLLDVGRFFTGYGIGVFSYVVPVYIAEISPKNLRGGLTTLNQLMIVIGSSVSFLIG-----SL 192

  Fly   209 INFVNLGLLALGPLQILM------PESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFL--TR 265
            |::..|.|..|.|..:|:      ||||.:....|:......:|:.|||:..|...|.|.:  :.
plant   193 ISWKTLALTGLAPCIVLLFGLCFIPESPRWLAKAGHEKEFRVALQKLRGKDADITNEADGIQVSI 257

  Fly   266 DPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFY---------------GLN 315
            ...|...:.|...|:.   ||..||:...:::.:.|:..|.....||               |..
plant   258 QALEILPKARIQDLVS---KKYGRSVIIGVSLMVFQQFVGINGIGFYASETFVKAGFTSGKLGTI 319

  Fly   316 MLDCLRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGL 380
            .:.|:::.     |..||.|        |:|:.|||||::.|:.||....|..|..|   :..|.
plant   320 AIACVQVP-----ITVLGTI--------LIDKSGRRPLIMISAGGIFLGCILTGTSF---LLKGQ 368

  Fly   381 T-VMSWI---ALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAF------ 435
            : ::.|:   |:..:.|:|..::.|:|.:.||:.:|:....::.:..|:|...||..|:
plant   369 SLLLEWVPSLAVGGVLIYVAAFSIGMGPVPWVIMSEIFPINVKGIAGSLVVLVNWSGAWAVSYTF 433

  Fly   436 -FVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQ 483
             |::.|       ..|..|.|::..|:..::|....:||||..:..:||
plant   434 NFLMSW-------SSPGTFYLYSAFAAATIIFVAKMVPETKGKTLEEIQ 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	117/462 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	44/162 (27%)
AT5G18840	NP_568367.1	MFS_GLUT6_8_Class3_like	45..473	CDD:340916	117/462 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920