DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and TMT3

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001190054.1	Gene:	TMT3 / 824312	AraportID:	AT3G51490	Length:	737	Species:	Arabidopsis thaliana

Alignment Length:	262	Identity:	62/262 - (23%)
Similarity:	116/262 - (44%)	Gaps:	51/262 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   272 REVRQGPLLGFKYKK---VRRSLARSLAIALLQKLCGALIFIFY--------GL-NMLDCLRIRR 324
            :||:.||  |::..|   |:|:|...:.:.:||:..|....::|        |: ::|..|.|..
plant   492 KEVKDGP--GWRELKEPGVKRALMVGVGLQILQQFAGINGVMYYTPQILEETGVSSLLTNLGISA 554

  Fly   325 EFGLILCLGL-ILGFLACFF----LVDRLGRR-------PLLIFSSAGIVFVSIYLGLHFKVWMT 377
            |...:|...| .|..|.|..    |:|..|||       |:||.|...:|..|:         :.
plant   555 ESASLLISALTTLLMLPCILVSMRLMDVTGRRSLMLSTIPILILSLVTLVIGSL---------VN 610

  Fly   378 MGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICW-- 440
            :|.::.:.|:...:.:::.|:..|.|::..:|.:|:....:|.| |..:||..:.....::.:
plant   611 LGGSINALISTASVTVYLSCFVMGFGAIPNILCSEIFPTSVRGL-CITICALTFWICDIIVTYTL 674

  Fly   441 ------FGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLG-GLINRPAVITF 498
                  .|..||      |.::||:.::..:|..:.:||||.:....|.:... |...:.|..:|
plant   675 PVMLKSIGIAGV------FGIYAIVCAVAWVFVYLKVPETKGMPLEVISEFFSVGAKQQDAAASF 733

  Fly   499 TS 500
            .|
plant   734 LS 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	58/243 (24%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392
TMT3	NP_001190054.1	MFS	9..>186	CDD:119392
TMT3	NP_001190054.1	MFS	<512..703	CDD:119392	45/206 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910