DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and VGT1

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_186959.2	Gene:	VGT1 / 821117	AraportID:	AT3G03090	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	526	Identity:	112/526 - (21%)
Similarity:	211/526 - (40%)	Gaps:	107/526 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSY 85
            ||...|::...:.|.|   :|....:  :......|:..:|:..||..:|.:..|..|:.
plant    22 SGGITAEKEPLLKENH---SPENYSV--LAAIPPFLFPALGALLFGYEIGATSCAIMSLK----- 76

  Fly    86 SFQPT--ELQW---SGVCILLTLGAALWCLPMGLMVR-----LLGCRRTILIQLLPNFLGWFLTV 140
              .||  .:.|   |.|.:.:....:|:...:|.:|.     ::|.|:.:::......:|..:||
plant    77 --SPTLSGISWYDLSSVDVGIITSGSLYGALIGSIVAFSVADIIGRRKELILAAFLYLVGAIVTV 139

  Fly   141 FARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLE 205
            .|....:|..||...||..|......|:|.||.:.::.||.|..:.|.:.:.|::..:.:. .|.
plant   140 VAPVFSILIIGRVTYGMGIGLTMHAAPMYIAETAPSQIRGRMISLKEFSTVLGMVGGYGIG-SLW 203

  Fly   206 LRIINFVNLGLLALGPLQILM-------PESPAYYV-----DHGNIPRAED----SLRFLRG--- 251
            :.:|:........:.|..::|       |.||.:.:     ..||....:.    ||..|||
plant   204 ITVISGWRYMYATILPFPVIMGTGMCWLPASPRWLLLRALQGQGNGENLQQAAIRSLCRLRGSVI 268

  Fly   252 ------QKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFI 310
                  |..:...|:..:..|...:..|:.:|        |..::|..:..:.|.|::.|....:
plant   269 ADSAAEQVNEILAELSLVGEDKEATFGELFRG--------KCLKALTIAGGLVLFQQITGQPSVL 325

  Fly   311 FYGLNML---------DCLRIRREFGLILCLGLILGFL------ACFFLVDRLGRRPLLIFSSAG 360
            :|..::|         |..||          .::||.|      ....::||:||||||:...:|
plant   326 YYAPSILQTAGFSAAADATRI----------SILLGLLKLVMTGVSVIVIDRVGRRPLLLCGVSG 380

  Fly   361 IVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSI 425
            :|.....||.::..:..:..     :|:..:.::||||....|.:.|::.:|:....:|..|.|:
plant   381 MVISLFLLGSYYMFYKNVPA-----VAVAALLLYVGCYQLSFGPIGWLMISEIFPLKLRGRGISL 440

  Fly   426 VCAFNWLTAFFVICWFGSHGVKCQPY-----------LFLLFAIIASLILLFSLIYIPETKKLSS 479
            ....|          ||::.:....:           ||..|.:|..:.|.|....:||||.|:.
plant   441 AVLVN----------FGANALVTFAFSPLKELLGAGILFCAFGVICVVSLFFIYYIVPETKGLTL 495

  Fly   480 AKIQQR 485
            .:|:.:
plant   496 EEIEAK 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	105/484 (22%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	37/172 (22%)
VGT1	NP_186959.2	MFS_GLUT10_12_Class3_like	53..498	CDD:340920	104/485 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820