DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and AT2G48020

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_566120.1	Gene:	AT2G48020 / 819414	AraportID:	AT2G48020	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	127/484 - (26%)
Similarity:	221/484 - (45%)	Gaps:	61/484 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RAPVRQKINNVG--------LYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWS 95
            |.|:..| |..|        :|.:|..:..|||.||...|:|..|:.::....|.:.....|..|
plant     9 REPLVDK-NMAGSKPDQPWMVYLSTFVAVCGSFAFGSCAGYSSPAQAAIRNDLSLTIAEFSLFGS 72

  Fly    96 GVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGG 160
                |||.||.:..:..|.:..|:|.:..:.:......:||...:||:.|..|..||...|...|
plant    73 ----LLTFGAMIGAITSGPIADLVGRKGAMRVSSAFCVVGWLAIIFAKGVVALDLGRLATGYGMG 133

  Fly   161 AHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVN--------LGLL 217
            |...||||:.|||:....|||:..:.:.....||..||.:...:..|::..:.        |||
plant   134 AFSYVVPIFIAEIAPKTFRGALTTLNQILICTGVSVSFIIGTLVTWRVLALIGIIPCAASFLGL- 197

  Fly   218 ALGPLQILMPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGF 282
                  ..:||||.:....|.....|.:||.|||:|.|...|...: :|..|:...:.:..:|..
plant   198 ------FFIPESPRWLAKVGRDTEFEAALRKLRGKKADISEEAAEI-QDYIETLERLPKAKMLDL 255

  Fly   283 KYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLIL--CLGLILGFLACFFLV 345
            ..::..||:..:..:.:.|:..|.....||..::.:........|:|:  .|.:::..|.. .:|
plant   256 FQRRYIRSVLIAFGLMVFQQFGGINGICFYTSSIFEQAGFPTRLGMIIYAVLQVVITALNA-PIV 319

  Fly   346 DRLGRRPLLIFSSAGIVF------VSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGS 404
            ||.||:|||:.|:.|:|.      ||.||.:|     .|....:..:|:..|.:::|.::||:|:
plant   320 DRAGRKPLLLVSATGLVIGCLIAAVSFYLKVH-----DMAHEAVPVLAVVGIMVYIGSFSAGMGA 379

  Fly   405 LTWVLNAELLVRPMRPLGCSIVCAFNWLTAF-------FVICWFGSHGVKCQPYLFLLFAIIASL 462
            :.||:.:|:....::.:...:....||..|:       |::.| .|:|.      ||::|.|.:|
plant   380 MPWVVMSEIFPINIKGVAGGMATLVNWFGAWAVSYTFNFLMSW-SSYGT------FLIYAAINAL 437

  Fly   463 ILLFSLIYIPETKKLSSAKIQQRLGGLIN 491
            .::|.:..:||||    .|..:::..::|
plant   438 AIVFVIAIVPETK----GKTLEQIQAIVN 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	119/446 (27%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	46/170 (27%)
AT2G48020	NP_566120.1	MFS_GLUT6_8_Class3_like	29..456	CDD:340916	121/455 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.920