Protein Alignment Glut3 and SLC2A10

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_011527362.1
• Gene: SLC2A10 / 81031
• HGNCID: 13444
• Length: 562
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 116/535 - (21%)
• Similarity: 188/535 - (35%)
• Gaps: 149/535 - (27%)

  Fly    62 SFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCI-------LLTLGAALWCLPMGLMVRLL 119
            |...|:..|:    |.:|:   |.:..|.:|.:...|:       .|.|||.|..|..|.::...
Human    36 SLLGGLTFGY----ELAVI---SGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLIDCY 93

  Fly   120 GCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGV 184
            |.::.||...|....|......|.|:..|..||..:|.......:...||.:|:...::||.:..
Human    94 GRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGPRQRGVLVS 158

  Fly   185 VFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGP--LQILMPESPAYYVDHGNIPRAEDSLR 247
            ::|.....|::.|:|::..|......:.::...|..|  ||.|                   ||.
Human   159 LYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSL-------------------SLL 204

  Fly   248 FLRGQKYDTRREIDFLTRDPTESEREVRQGP-------LLGFKYK-KVRRSLARSLAIALLQKLC 304
            ||.....:|....|.:   |.:.....:.||       |..|:.: .:|......|.:.|.|:|.
Human   205 FLPAGTDETATHKDLI---PLQGGEAPKLGPGRPRYSFLDLFRARDNMRGRTTVGLGLVLFQQLT 266

  Fly   305 GALIFIFYGLNMLDCLRIRREFGLILC-LGL----ILGFLACFFLVDRLGRRPLLI-------FS 357
            |....:.|...:...:........:|. :||    :...|....||||.|||.||:       .|
Human   267 GQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGLVDRAGRRALLLAGCALMALS 331

  Fly   358 SAGIVFVSIYLGLHFKVWM---------------------------------------------- 376
            .:||..||      |.|.|
Human   332 VSGIGLVS------FAVPMDSGPSCLAVPNATGQTGLPGDSGLLQDSSLPPIPRTNEDQREPILS 390

  Fly   377 --------------------------------TMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVL 409
                                            ..|..::.|.||.|:.:||..::.|.|.:||::
Human   391 TAKKTKPHPRSGDPSAPPRLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLV 455

  Fly   410 NAELLVRPMRPLGCSIVCAFNWLTAFFVICWF----GSHGVKCQPYLFLLFAIIASLILLFSLIY 470
            .:|:....:|....:...:|||....|:...|    |:.|:.   :.|||:.:.|.|.|.|..::
Human   456 LSEIYPVEIRGRAFAFCNSFNWAANLFISLSFLDLIGTIGLS---WTFLLYGLTAVLGLGFIYLF 517

  Fly   471 IPETKKLSSAKIQQR 485
            :||||..|.|:|.|:
Human   518 VPETKGQSLAEIDQQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	112/526 (21%)
SLC2A10	XP_011527362.1	MFS_GLUT10_Class3	31..529	CDD:340994	114/530 (22%)