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Protein Alignment Glut3 and SLC2A5

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001315548.1	Gene:	SLC2A5 / 6518	HGNCID:	11010	Length:	501	Species:	Homo sapiens

Alignment Length:	461	Identity:	120/461 - (26%)
Similarity:	200/461 - (43%)	Gaps:	65/461 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 YKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPMGLMV 116
            |..|.|...|.|                ||..     |..|.||....:...|..:..|.:|.:|
Human    50 YNETYYGRTGEF----------------MEDF-----PLTLLWSVTVSMFPFGGFIGSLLVGPLV 93

  Fly   117 RLLGCRRTIL----IQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTK 177
            ...|.:..:|    ..::|..|.....| |.|..::...|..:|:|.|....|||:|..|::...
Human    94 NKFGRKGALLFNNIFSIVPAILMGCSRV-ATSFELIIISRLLVGICAGVSSNVVPMYLGELAPKN 157

  Fly   178 KRGAMGVVFEGACICGVIYSFAMSLFLELRIINF--VNLGLLAL-GPLQILM----PESPAY-YV 234
            .|||:|||.:.....|::.:....|...|..::.  :.|||..: ..||:|:    ||||.| .:
Human   158 LRGALGVVPQLFITVGILVAQIFGLRNLLANVDGWPILLGLTGVPAALQLLLLPFFPESPRYLLI 222

  Fly   235 DHGNIPRAEDSLRFLRGQKYDT-RREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIA 298
            ...:...|:.:|:.|||  :|: .||:..:.:   |.|.|...|.:...|..::|....:.|:|.
Human   223 QKKDEAAAKKALQTLRG--WDSVDREVAEIRQ---EDEAEKAAGFISVLKLFRMRSLRWQLLSII 282

  Fly   299 LL---QKLCGALIFIFYGLNMLDCLRIRREFGLILCLG-----LILGFLACFFLVDRLGRRPLLI 355
            :|   |:|.|.....:|...:.....:..|....:..|     :::.|.| .|:|:.||||.||:
Human   283 VLMGGQQLSGVNAIYYYADQIYLSAGVPEEHVQYVTAGTGAVNVVMTFCA-VFVVELLGRRLLLL 346

  Fly   356 --FSSAGIV--FVSIYLGLHFKV-WMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLV 415
              ||...|.  .::..|.|...| |       |.:|::.|:..:|..:..|...:..:|..|:.:
Human   347 LGFSICLIACCVLTAALALQDTVSW-------MPYISIVCVISYVIGHALGPSPIPALLITEIFL 404

  Fly   416 RPMRPLGCSIVCAFNWLTAFFV--ICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLS 478
            :..||....:..:.:||:.|.|  |..|...|:  .||.|::||:|..|..::..:.:||||..:
Human   405 QSSRPSAFMVGGSVHWLSNFTVGLIFPFIQEGL--GPYSFIVFAVICLLTTIYIFLIVPETKAKT 467

  Fly   479 SAKIQQ 484
            ..:|.|
Human   468 FIEINQ 473

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.