Protein Alignment Glut3 and Slc2a5

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_062715.2
• Gene: Slc2a5 / 56485
• MGIID: 1928369
• Length: 501
• Species: Mus musculus
• Alignment Length: 494
• Identity: 129/494 - (26%)
• Similarity: 211/494 - (42%)
• Gaps: 63/494 - (12%)

  Fly    32 MPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSVME--QHSY--------- 85
            |.|:|.|.......:    |..|||.:..||.|   ..|::..|..|..|  |..|
Mouse     1 MEEKHQEETGELTLV----LALATLIAAFGSSF---QYGYNVAAVNSPSEFMQQFYNDTYYDRNE 58

  Fly    86 ----SFQPTELQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTIL----IQLLPNFLGWFLTVFA 142
                ||..| |.||....:...|..:..|.:|.:|..||.:..:|    ..:||..| ...:..|
Mouse    59 ENIESFTLT-LLWSLTVSMFPFGGFIGSLMVGTLVNKLGRKGALLFNNIFSILPAIL-MGCSQIA 121

  Fly   143 RSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLF-LEL 206
            :|..::...|..:|:|.|....|||:|..|::....|||:|||.:.....|::.:   .|| |..
Mouse   122 QSFELIIISRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVA---QLFGLRS 183

  Fly   207 RIINF----VNLGLLAL-GPLQILM----PESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREID 261
            .:.|.    |.|||..: ..||:|:    ||||.| .:...:...||.:|:.|||.| |...|::
Mouse   184 LLANEDGWPVLLGLTGVPAGLQLLLLPFFPESPRYLLIQKKDEAAAERALQTLRGWK-DVHLEME 247

  Fly   262 FLTRDPTESEREVRQGPLLGFK---YKKVRRSLARSLAIALLQKLCGALIFIFY--------GLN 315
            .:.:   |.|.|...|.:..:|   .:.:|..|...:.:...|:|.|.....:|        |:.
Mouse   248 EIRK---EDEAEKAAGFISVWKLFTMQSLRWQLISMIVLMAGQQLSGVNAIYYYADQIYLSAGVK 309

  Fly   316 MLDCLRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGL 380
            ..|...:....|.:.....||    ..|:|:..|||.||:...:..:...:.|.....:..|  :
Mouse   310 SDDVQYVTAGTGAVNVFMTIL----TIFVVELWGRRFLLLVGFSTCLIACLVLTAALALQNT--I 368

  Fly   381 TVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHG 445
            :.|.:|::.|:.::|..:..|...:..:|..|:.::..||....|..:.:||:.|.|...|....
Mouse   369 SWMPYISIVCVIVYVIGHALGPSPIPALLITEIFLQSSRPAAYMIGGSVHWLSNFTVGLIFPFIQ 433

  Fly   446 VKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQ 484
            :...||.|::||.|..|..::..:.:||||..:..:|.|
Mouse   434 MGLGPYSFIIFATICFLTTIYIFMVVPETKGRTFIEINQ 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	122/466 (26%)
Slc2a5	NP_062715.2	MFS_GLUT_Class2	22..470	CDD:340990	119/465 (26%)