Protein Alignment Glut3 and slc2a2

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001011453.1
• Gene: slc2a2 / 496943
• XenbaseID: XB-GENE-486462
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 123/493 - (24%)
• Similarity: 218/493 - (44%)
• Gaps: 67/493 - (13%)

  Fly    42 VRQKINNVG-LYKATLYSNIGSFFFGIAVGWSGTAERSVMEQHSYS---FQPTELQ--------- 93
            ::|:.|..| |..|...:.:.|..||..:|.. .|.:.::|.| |:   .:.:|.|
 Frog     1 MKQQKNLTGTLVFAVFTAVLASLQFGYGIGVI-NAPQKIIENH-YTRVLLEGSENQTDTTPVQSS 63

  Fly    94 ----WSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFA---RSVPMLYAG 151
                ||....:.:||..:....:|.:...||..:.:::..:...:|..|...|   ::..::.||
 Frog    64 VKMYWSLSVSVFSLGGMVSSFFVGWIADKLGRIKAMMVVNILAVIGALLMGLAPLGQAHALVIAG 128

  Fly   152 RFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVNLGL 216
            |...|:..|....:||:|..|||.|..|||:|.:.:.|.:.|::.|..:.|..   |:...:|..
 Frog   129 RLITGLYCGLASGLVPMYVGEISPTALRGALGTLHQLAIVTGILISQVVGLEF---ILGSEHLWP 190

  Fly   217 LALG----P------LQILMPESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTES 270
            :.||    |      |....||||.: .:..|....|:.:|..|||: ||..::|:.:.::..|:
 Frog   191 VLLGLSGVPAVVQTILLFFCPESPRFLLIKLGKTEAAKRNLIKLRGE-YDPTKDIEEMKKEKEEA 254

  Fly   271 EREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLI 335
            |.|.:...:..||....|:.|..||.:.:.|:..|.....:|..::.....|.:.....:.:|.:
 Frog   255 ESEKKVSIIQLFKSSNYRQPLVVSLVLHISQQFSGINGIFYYSTSIFTRAGISQPVYATIGVGAV 319

  Fly   336 --LGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTV------MSWIALFCIA 392
              :..:...|||::.|||.|.:....|:...:|.        ||:.|.:      ||:::|..|.
 Frog   320 NTVFTVVSVFLVEKAGRRSLYLVGLGGMCICAIV--------MTIALALLTQHAWMSYLSLVAIF 376

  Fly   393 IFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFA 457
            :||..:..|.|.:.|.:.|||..:..||...::....||...|.:...|......|.||:|::||
 Frog   377 LFVVFFEVGPGPIPWFIVAELFSQGPRPAAMAVSGCCNWTCNFIIGMCFEYIADACGPYIFIIFA 441

  Fly   458 IIASLILLFSLIYIPET--------------KKLSSAK 481
            ::..:..:|:...:|||              ||||:.|
 Frog   442 VLLLIFTVFTYFKVPETKGKSFDEIAAEFRKKKLSTRK 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	116/477 (24%)
slc2a2	NP_001011453.1	MFS_GLUT_Class1	13..461	CDD:340989	114/461 (25%)