DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and CG10960

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_648605.1	Gene:	CG10960 / 39458	FlyBaseID:	FBgn0036316	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	465	Identity:	145/465 - (31%)
Similarity:	240/465 - (51%)	Gaps:	33/465 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 YKATLYSNIGSFFFGIAVGWSGTAERSVMEQ-HSYSFQPTELQWSGVCILLTLGAALWCLPMGLM 115
            |.|.|.:..|:|..|..:||:..||..:::: ..|.|...:.|:|.|...:|||||..|:|:|.:
  Fly    84 YVAALAAAGGAFAAGTVLGWTSPAETEIVDRGEGYDFPVDKDQFSWVGSAMTLGAACVCIPIGFL 148

  Fly   116 VRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRG 180
            :.::|.:.|:|..:||..|||.:.::|.:|.||||.||.||:.|||.||..|:|..||:..:.||
  Fly   149 INMIGRKWTMLFLVLPFILGWTMLIWAVNVSMLYASRFILGIAGGAFCVTAPMYTGEIAQKEIRG 213

  Fly   181 AMGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLAL--GPLQILMPESPAYYVDHGNIPRAE 243
            .:|..|:.....|:::.:|:...:::..::.: .|:|.|  |.:...|||||.|.|.......|.
  Fly   214 TLGSFFQLMITIGILFVYAVGAGVKIFWLSII-CGILPLIFGAIFFFMPESPTYLVSKDRSENAI 277

  Fly   244 DSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPL---LGFKYKKVRRSLARSLAIALLQKLCG 305
            .|:::|||::||...|:..|    .|::||.:...:   ........|::||.|:.:...|::||
  Fly   278 KSIQWLRGKEYDYEPELAEL----RETDRETKANKVNVWAALNRPVTRKALAISMGLMFFQQVCG 338

  Fly   306 ALIFIFYGLNM-LDC-LRIRREFGLILCLGLILGFLACF---FLVDRLGRRPLLIFSSAGIVFVS 365
            ....|||...: |:. ..|..|:..|| :| |:..:|.|   .:||:||||.||:.|...:...:
  Fly   339 INAVIFYASRIFLEANTGIEAEWATIL-IG-IMQVVATFVSTLVVDKLGRRILLLASGISMAIST 401

  Fly   366 IYLGLHFKVWMTMGLTVMS--WIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCA 428
            ..:|::|.:.......|:|  |:.:..:.:|:..::.|.|.:.|::..||....::....|:...
  Fly   402 TAIGVYFFLQKQDAAQVVSLGWLPVASLCLFIIMFSIGYGPVPWLMMGELFATDIKGFAGSLAGT 466

  Fly   429 FNWLTAFFVICWF-------GSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRL 486
            .|||.||.|...|       |..|.      |.|||.:..:.::|....:||||..|..:|||.|
  Fly   467 SNWLLAFVVTKTFVNLNDGLGIGGT------FWLFAGLTVVGVIFVYFAVPETKGKSLNEIQQEL 525

  Fly   487 GGLINRPAVI 496
            .|..:.|..|
  Fly   526 AGNRSTPQAI 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	136/443 (31%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	56/165 (34%)
CG10960	NP_648605.1	MFS_1	117..474	CDD:284993	113/363 (31%)
CG10960	NP_648605.1	MFS	118..508	CDD:119392	123/402 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444279
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	1	1.000	-	-		FOG0000275
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	8	7.850