DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and CG32053

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	554	Identity:	129/554 - (23%)
Similarity:	195/554 - (35%)	Gaps:	172/554 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ERHVERAPVRQK----------------------INNVGLYKATLYSNIGSFFFGIAVGWSGTAE 76
            |:|:.|...||:                      .|.||  .|.|....|    |:.:.||...:
  Fly    22 EQHIHRNSDRQRELILQNSQTSPCCNRDLRNQPQANAVG--AAALIFLTG----GVHIAWSIGFD 80

  Fly    77 RSVMEQHSYSFQPTELQWSG-VCILLTLGAALWCLPMGLMVRLLGCRRTI-LIQLLPNFLGWFLT 139
            .|:          :||:.:. |.|...:||.:..|..|...|....:..: ...|:....|..:.
  Fly    81 SSL----------SELEVTNHVQICWFIGAIIGALLGGFFSRWFPYKTLMEFCSLITITGGIVMA 135

  Fly   140 VFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRG-----------AMGVVFEGACICG 193
            |....:..|.|||:..|:..|...........|:|...|||           .:|:..:..|
  Fly   136 VNRMDLDALLAGRYMNGLANGLAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVC--- 197

  Fly   194 VIYSF-AMSLFLELRIINFVN--LGLLALGPLQILMPESPAYYVDHGNIPRAEDSL------RFL 249
             .:|: ..|.|.|.:....::  ||.:||....:|..|||...::.||...|..:|      |.:
  Fly   198 -SHSWDVQSDFTEEQFQGVLSGVLGSIALLLAFLLSIESPVDLLEQGNEQGAVQALSRLQRPRAV 261

  Fly   250 RGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKY---KKVRRSLARSL-AIALLQKLCGALI-- 308
            ..:.||..|:    .|...|..|.      :|:::   ..||.|:.|:| |::|...:...|.
  Fly   262 TAETYDQVRD----HRTYVEHHRS------MGWRHALPALVRLSVLRALYALSLSVMVAFTLAWT 316

  Fly   309 -----------FIFYGLNMLDCLRIRREF-----------GLILCLGLIL-GFLACFFLVDRLGR 350
                       ::.:|.     ||:...|           .:.|.|||:: |.|||.......|.
  Fly   317 STEVYGDSSGPYVLFGF-----LRLMGSFTTSFALDSLGRKIPLLLGLVISGCLACGLASRFAGS 376

  Fly   351 RP------------LLIFS-SAGIVFV--SIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTA 400
            .|            |||:. .|||.|.  |.||...|.          ..|...||||
  Fly   377 HPLTFSGNRMALWLLLIYQLFAGIAFAPSSSYLSEAFP----------RRIKRPCIAI------- 424

  Fly   401 GVGSLTWVLN--AELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLI 463
                 |::|.  .:||:|.|               .|..|   ||.    ..|:.|.|.|:..|:
  Fly   425 -----TYILEIIVQLLLRQM---------------DFAAI---GSD----SSYVALYFFILGGLL 462

  Fly   464 L---LFSLIYIPETKKLSSAKIQQRLGGLINRPA 494
            |   |||:.|:||||..:..:.|.:....:..||
  Fly   463 LAGFLFSVWYMPETKDTTLLQAQFKFQEFVIPPA 496

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	116/494 (23%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	37/178 (21%)
CG32053	NP_729587.1	MFS	73..428	CDD:119392	91/405 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444375
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830