DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Glut3 and CG15406

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_608761.2	Gene:	CG15406 / 33542	FlyBaseID:	FBgn0031517	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	476	Identity:	121/476 - (25%)
Similarity:	196/476 - (41%)	Gaps:	89/476 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 TLYSNIGSFFFGIAVGW-SGTAERSVMEQH---SYSFQPTELQWSGVCILLTLGAALWCLPMGLM 115
            :|.:.:.:|..|||:|| |....:.:..|.   |:.....|..|.|.  ::::|..........:
  Fly    22 SLSATLITFCHGIALGWLSPMLPKLLSPQETPLSFYIDVNEASWLGA--VISIGGISGNFSFSYL 84

  Fly   116 VRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRG 180
            :...|.:.:|....:|:...|||..||:|:..||..|.|.|:.||...||:||:..||:....||
  Fly    85 MNRFGRKVSIYALAVPHTCIWFLFYFAQSIEWLYVARVFAGLTGGGMFVVLPIFIGEIADNSIRG 149

  Fly   181 AMGVVFEGACICGVIYSFAMSLFLELRIINFVNLGLLALGPLQILM----PESPAYYVDHGNIPR 241
            .:...|......|::..|.:|..:...:|....:||..   |.:|:    ||.|...:.......
  Fly   150 RLCSFFTLTMNTGIMVGFVVSSHIAYHVIPCAVVGLPV---LYVLLATRYPEPPQQLIRWKREEE 211

  Fly   242 AEDSLRFLRG--------------QKY--DTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRS 290
            ||.|||:.|.              ||:  :.|..|.....|..::...:..     |..|:..::
  Fly   212 AEKSLRYYRRCDGPNVSKEEERAYQKHFDEMRLAIQQQNNDTDDNGLSMSD-----FLTKRSLKA 271

  Fly   291 LARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFG---LILCLGLILGFLACFFLVDRLGRRP 352
            ||..|.:.:.....|...|..|..|:.|.:..:.:..   :|:....|||.||..:||||.||:.
  Fly   272 LATGLVLMVANIFTGTFAFNNYMSNIFDAVHTQLDPNTNTIIIGAVQILGTLASIYLVDRYGRKI 336

  Fly   353 LLIFSSAGIVFVSIYLGLH-------------FKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGS 404
            |||.|.||....:...||:             |..|:.  :|:|::|      ||:.  ..||.|
  Fly   337 LLIVSCAGSGIGTSAFGLYAFYAEEQKVDLSAFSAWLP--VTLMAFI------IFIA--NVGVIS 391

  Fly   405 LTWVLNAELLVRPMRP------LGCSIVCAFNWLTAFFVI---------CWFGSHGVKCQPYLFL 454
            :|.|:..|:|.:.:|.      |||....||..|..|.::         .||      |
  Fly   392 VTMVVLVEILPQKIRAVATSFCLGCLSFFAFASLKTFPLMMFHLGLAATMWF------C------ 444

  Fly   455 LFAIIASLILLFSLIYIPETK 475
              |.::.:.|.:.::.:.|||
  Fly   445 --AAVSVICLFYVVVCLEETK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	120/471 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	45/166 (27%)
CG15406	NP_608761.2	MFS	23..458	CDD:119392	118/468 (25%)
CG15406	NP_608761.2	SP	26..466	CDD:273317	120/472 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444366
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	6	5.850