Protein Alignment Glut3 and Slc2a2

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_112474.2
• Gene: Slc2a2 / 20526
• MGIID: 1095438
• Length: 523
• Species: Mus musculus
• Alignment Length: 479
• Identity: 121/479 - (25%)
• Similarity: 210/479 - (43%)
• Gaps: 88/479 - (18%)

  Fly    59 NIGSF--------FFGIAVGWSGT---AERSVMEQHSYSFQPTELQWSGVCILLTLGAALWCLPM 112
            ::.||        |||   ||.|.   ..::::..:|                |:|..||
Mouse    99 SVSSFAVGGMVASFFG---GWLGDKLGRIKAMLAANS----------------LSLTGAL----- 139

  Fly   113 GLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTK 177
                 |:||.:                 |..:..::.|||...|:..|....:||:|..||:.|.
Mouse   140 -----LMGCSK-----------------FGPAHALIIAGRSVSGLYCGLISGLVPMYIGEIAPTT 182

  Fly   178 KRGAMGVVFEGACICGVIYS--FAMSLFLELRIINFVNLGLLAL-GPLQILM----PESPAY-YV 234
            .|||:|.:.:.|.:.|::.|  ..:|..|..:....:.|||.|: ..||.|:    ||||.| |:
Mouse   183 LRGALGTLHQLALVTGILISQIAGLSFILGNQDHWHILLGLSAVPALLQCLLLLFCPESPRYLYI 247

  Fly   235 DHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIAL 299
            ......||:.||:.|||.: |..::|:.:.::..|:..|.:...:..|.....|:.:..:|.:.:
Mouse   248 KLEEEVRAKKSLKRLRGTE-DVTKDINEMKKEKEEASTEQKVSVIQLFTDANYRQPILVALMLHM 311

  Fly   300 LQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGLI-LGFLA-CFFLVDRLGRRPLLIFSSAGIV 362
            .|:..|.....:|..::.....|.:.....:.:|.| :.|.| ...||::.|||.|.:....|:.
Mouse   312 AQQFSGINGIFYYSTSIFQTAGISQPVYATIGVGAINMIFTAVSVLLVEKAGRRTLFLTGMIGMF 376

  Fly   363 FVSIYLGLHFKVWMTMGLTV------MSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPL 421
            |.:|:        |::||.:      ||::::..|.:||..:..|.|.:.|.:.||...:..||.
Mouse   377 FCTIF--------MSVGLVLLDKFAWMSYVSMTAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPT 433

  Fly   422 GCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLS----SAKI 482
            ..::....||:..|.:...|........||:|.|||.:..:..||:...:||||..|    :|:.
Mouse   434 ALALAAFSNWVCNFVIALCFQYIADFLGPYVFFLFAGVVLVFTLFTFFKVPETKGKSFEEIAAEF 498

  Fly   483 QQRLGGLINRPAVI--TFTSSSDS 504
            :::.|....|.|.:  .|.:||:|
Mouse   499 RKKSGSAPPRKAAVQMEFLASSES 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	112/445 (25%)
Slc2a2	NP_112474.2	MFS_GLUT_Class1	12..489	CDD:340989	112/444 (25%)