DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Glut3 and srx-118

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_496675.2	Gene:	srx-118 / 188681	WormBaseID:	WBGene00006009	Length:	328	Species:	Caenorhabditis elegans

Alignment Length:	222	Identity:	49/222 - (22%)
Similarity:	91/222 - (40%)	Gaps:	55/222 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 LAIALLQKLCGALIFI--FYGLNMLD------CLRIRREFG-LILCLGLILGFLACFFLVDRLGR 350
            :.::::..:...||||  |:.:...|      |.   ..|| .|:|    :|:||  |.|
Worm    27 IVVSIIGSIMNVLIFIATFFRVTKRDGFLKICCF---NSFGSCIVC----IGYLA--FPV----- 77

  Fly   351 RPLLIFSSAGIVFVSIYLGLHFKVWM--TMG------LTVMSWIALFCIAIFVGCY-----TAGV 402
             |.|:.......:::..:| .|..|.  ::|      |||...||::...:::..|     ..|:
Worm    78 -PSLLLEDPPNHWLNAAMG-QFIAWFGWSIGPLSQILLTVNRIIAVYFPLLYMKKYRYNPTNVGI 140

  Fly   403 GSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSH----GVKCQPYLFLLFAIIA--- 460
            |...:|  |.:|:....|.||..:...::|.      |.|..    .:..:.:|.::..|.|
Worm   141 GFSFFV--AFILLVSFFPEGCHYLFNRDYLG------WVGEFTPCIDIMQKTFLVVMMTICALTT 197

  Fly   461 --SLILLFSLIYIPETKKLSSAKIQQR 485
              |::|...||......::|:|::..|
Worm   198 CCSVLLFIKLIIHSPNFRVSNAQLANR 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	48/219 (22%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392
srx-118	NP_496675.2	7TM_GPCR_Srx	27..285	CDD:370981	49/222 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010