Protein Alignment Glut3 and hmit-1.2

DIOPT Version :9

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_507624.1
• Gene: hmit-1.2 / 180206
• WormBaseID: WBGene00013074
• Length: 613
• Species: Caenorhabditis elegans
• Alignment Length: 604
• Identity: 128/604 - (21%)
• Similarity: 219/604 - (36%)
• Gaps: 151/604 - (25%)

  Fly    41 PVRQKINNVGLYKATLYSN--IGSFFFGIAVGWSGTAERSVMEQHSYSFQPTELQWSGVCILLTL 103
            |..:|...:|.:...|.|.  ||.|.||........|...|.|  :...:|....|..|.:.:|.
 Worm    14 PRPEKNPKLGFFVYLLGSAAIIGGFLFGYDTSVVSAAMLYVPE--APGLKPMGTVWKEVIVSITP 76

  Fly   104 G-AALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVP 167
            | ||:.....|......|.:..|:...|....|..:...|.:..::..||.|||:..|...:|||
 Worm    77 GMAAVGAWFSGAGSDRYGRKPIIIGSTLIFVCGAVICAVAWTKIVMLIGRIFLGVGIGFASMVVP 141

  Fly   168 IYNAEISTTKKRG------AMGVVFEG--ACICGVIYSFAMSLFLELRIINFVNLGLLALGPLQ- 223
            :|..|.|.|..||      ||.:.|..  |.|.|.::|:.....:..|:: |...|:.||  :|
 Worm   142 VYLGEASPTHVRGTLVSAFAMMISFGQVVANIMGGVFSYWEPYTIGWRLM-FAFAGIPAL--IQF 203

  Fly   224 ---ILMPESPAYYVDHGNIPRAEDSLRFLRGQ-----KYDTRREIDFLTRDPTESEREVRQGPLL 280
               |.:||:|.:..::|:..:||..|..:.|.     :|:......:......:.|.|.:.||::
 Worm   204 VCFIFLPETPRWLYENGHTEQAEQVLEKIYGGNTEWIEYELAEIKTYAEERQKQMEEEKKSGPVI 268

  Fly   281 G--FKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRRE-----FGLILCLGLILGF 338
            .  .|...|.::......:...|:|.|....::|..:::....|...     ..:||.:..::|.
 Worm   269 WRILKTPHVLKACFIGSMLQAFQQLAGINTILYYTADIIRSAGIENYHTIIWISVILSICNLIGP 333

  Fly   339 LACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHF------------------------------- 372
            .|..|.:::||||.|.:||.||:|...:.:|:.|
 Worm   334 FAPMFFIEKLGRRKLFLFSCAGVVVSLVLIGVSFLLVGNDSAPNFDRSAYLLAGNYQSNGEAESC 398

  Fly   373 ------------------------------------KVWMTMGL---------------TVMSW- 385
                                                .::.:.||               |...|
 Worm   399 LMLSNCDSCVTSEHCGFCEDSETRTGFCLPVDHNDVTLYSSTGLCTNGLDKSNSSFPNATSYVWQ 463

  Fly   386 ----------IALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNW--------- 431
                      :.:..:.:::..::.|..||.||||:|......|....||....||
 Worm   464 KHHCTTSYTILPIVMMGVYLLTFSCGFTSLPWVLNSEFYPMWARSTCVSISTLSNWVFNLIIALT 528

  Fly   432 -LTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQ-------QRLGG 488
             |:....|..:|:.      :|:.:|.|||.:.:.|   .:|||...|..:::       ||...
 Worm   529 YLSLTHAITKYGAF------WLYAIFTIIAFIFIYF---LVPETTGYSIDEVEMLFMNKRQRNIA 584

  Fly   489 LINRPAVITFTSSSDSSNA 507
            :..|.|.:...|..|.:::
 Worm   585 MQARQAKLDAASDKDKNSS 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	117/558 (21%)
		MFS	63..>226	CDD:119392	48/175 (27%)
hmit-1.2	NP_507624.1	MFS	32..562	CDD:421695	113/543 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157952
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4448
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.700