Protein Alignment Glut3 and hmit-1.3

DIOPT Version :9

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_497725.2
• Gene: hmit-1.3 / 175458
• WormBaseID: WBGene00010811
• Length: 604
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 131/590 - (22%)
• Similarity: 210/590 - (35%)
• Gaps: 160/590 - (27%)

  Fly    15 PQSSRKSGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWSGTAERSV 79
            |.|..|:| ||                         :|.....:.||.|.||...|....|...|
 Worm    18 PSSDPKTG-WF-------------------------VYMLAFSAVIGGFLFGYDTGIVSAAMLYV 56

  Fly    80 MEQHSYSFQPTELQWSGVCILLTLG-AALWCLPMGLMVRLLGCRRTILIQLLPNF-LGWFLTVFA 142
              .::...:|.:..|..:.:.:|.| ||:..|..|.....|| |:.|:|.....| :|..:...|
 Worm    57 --PNASGIKPLDSVWQEIIVSITPGVAAIGSLCSGPGSDFLG-RKKIIIGASVTFTIGAIICAAA 118

  Fly   143 RSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFE-----GACICGVI---YSFA 199
            .:..:|..||..||:..|...::||||.:|.|.:..||.:...|:     |..|..:|   :|:.
 Worm   119 WTKIILLIGRILLGLAIGFASMIVPIYVSEASPSHIRGKLVTGFQLMITVGLVIANIIGGAFSYV 183

  Fly   200 ---------MSLFLEL-RIINFVNLGLLALGPLQILMPESPAYYVDHGNIPRAEDSL-RFLRGQ- 252
                     |..|..: .||.||..         :.:||||.:..:||....|.:.| |...|.
 Worm   184 DPDQVGWRLMFAFAAVPAIIQFVCF---------LFLPESPRWLYEHGRTVEAREVLTRIYNGHT 239

  Fly   253 ---KYDTRREIDFLTRDPTESERE-VRQGPLL--GFKYKKVRRSLARSLAIALLQKLCGALIFIF 311
               .|:. .||.|...:...::.| ...||.:  ..|...||:::.....:.:.|:|.|....::
 Worm   240 EWVDYEI-NEISFSYEEELRAKAEHAGNGPTIIRILKTPHVRKAMIIGSLLQMFQQLSGINTVMY 303

  Fly   312 YGLNMLDCLRIRREFGLI-LCLGL-ILGFLACFF---LVDRLGRRPLLIFSSAGIVFVSIYLGLH 371
            |..|::....::.....| :.:|. .:.||..|.   ||:|:|||.||:.|..|::...|.:|:.
 Worm   304 YTGNIIRSAGVKDNHTTIWISVGTSAINFLGTFIPIALVERVGRRVLLLVSMIGVILFLIAMGVS 368

  Fly   372 F--------------------------------------------------KV------------ 374
            |                                                  ||
 Worm   369 FLLINNDSLRTFDQQNYTLNYNPSVKHAAKCLKYSNCDFCVTDENCGFCESKVAKKGYCLPFPSD 433

  Fly   375 ----WMTMGL----------TVMSWIALFC-----------IAIFVGCYTAGVGSLTWVLNAELL 414
                :...|:          |...|...:|           :..::..::||...|.||||||..
 Worm   434 DSSDYSATGICEFSNLTNNGTDFEWEDTYCHTKFTVLPIIIMVFYLLSFSAGYAPLPWVLNAEFY 498

  Fly   415 VRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPY-LFLLFAIIASLILLFSLIYIPETKKLS 478
            ....|....|:..|.||:....|...|.|.......| .|.::.....:.|:|...::||||..|
 Worm   499 PLWARSTAVSVSTACNWIFNLIVSLTFLSLSQAATKYGTFFIYCGCTMVALVFVFFFVPETKGYS 563

  Fly   479 SAKIQ 483
            ..:::
 Worm   564 IDEVE 568

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	124/545 (23%)
		MFS	63..>226	CDD:119392	47/182 (26%)
hmit-1.3	NP_497725.2	MFS	34..558	CDD:421695	119/536 (22%)
		MFS	<190..>249	CDD:421695	17/68 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830