Protein Alignment Glut3 and SLC2A7

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_011539126.1
• Gene: SLC2A7 / 155184
• HGNCID: 13445
• Length: 517
• Species: Homo sapiens
• Alignment Length: 464
• Identity: 116/464 - (25%)
• Similarity: 194/464 - (41%)
• Gaps: 78/464 - (16%)

  Fly    18 SRKSGTWFAKRPSEMPERHVERAPVRQKINNVGLYKATLYSNIGSFF-FGIAVGWSGTAER---- 77
            ::::||     |..:|.|.....|.        |..|||.:..||.| :|..:....|..:
Human     3 NKEAGT-----PPPIPSREGRLQPT--------LLLATLSAAFGSAFQYGYNLSVVNTPHKVFKS 54

  Fly    78 ----SVMEQHSYSFQPTELQ---WSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQ----LLP 131
                :..|:|: :|...:|.   ||....:..||..|..|.:||:|...|.:.|:||.    ::|
Human    55 FYNETYFERHA-TFMDGKLMLLLWSCTVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIP 118

  Fly   132 NFLGWFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIY 196
            ..| ..::..|::..::...|..||:|.|.....:|:|..|::....||.:|.:.|...|.||
Human   119 AIL-MGVSKVAKAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGV-- 180

  Fly   197 SFAMSLFLELRIINFVNLG-------LLAL----GPLQIL----MPESPAY-YVDHGNIPRAEDS 245
             |...:| .|:.|    ||       ||||    ..||:|    .||||.| .:..|:...|..:
Human   181 -FLAQIF-SLQAI----LGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQA 239

  Fly   246 LRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALL---QKLCGAL 307
            ||.|||.. |...|::.:.   .|:..|..:|.|.......:|....:.|:|.:|   |:|.|..
Human   240 LRRLRGHT-DMEAELEDMR---AEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGIN 300

  Fly   308 IFIFYGLNMLDCLRIRREFGLILCLGL----ILGFLACFFLVDRLGRRPLL-----IFSSAGIVF 363
            ...:|...:.....:.......:.:|.    |:..:....||:|||||.||     |..||.:|.
Human   301 AINYYADTIYTSAGVEAAHSQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVL 365

  Fly   364 VSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCA 428
            ..:.|       ....:..:|::.:.|:..::..::.|...:..|:..|:.::..|.....:..|
Human   366 TVVLL-------FQNRVPELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGA 423

  Fly   429 FNWLTAFFV 437
            .:|||.|.:
Human   424 VHWLTNFII 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	109/430 (25%)
SLC2A7	XP_011539126.1	MFS_GLUT_Class2	26..440	CDD:340990	109/428 (25%)