DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and slc2a11l2

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001339155.2	Gene:	slc2a11l2 / 110386950	-ID:	-	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	476	Identity:	102/476 - (21%)
Similarity:	182/476 - (38%)	Gaps:	59/476 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 GLYKATLYSNIGSFF-FGIAVGWSGT--------AERSVMEQHSYSF-QPTE-LQWSGVCILLTL 103
            ||:.......|||.| :|..:....:        ...|.|.:|..:. |.|. |.||....:.::
Frog    13 GLFFMAFIMGIGSTFQYGYQISVLNSPSPFIKQFINESWMRRHETTITQGTHTLIWSLTVSVFSI 77

  Fly   104 GAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSV---PMLYAGRFFLGMCGGAHCVV 165
            |..:..:..|.:...||.::.:|.......:...|...:::|   .::..|||..|:..|....:
Frog    78 GCLIGSVSSGYLSGKLGKKKCMLYNTFLPLINTVLMGLSQTVGLFELIIVGRFLCGIYVGLGLNI 142

  Fly   166 VPIYNAEISTTKKRG------AMGVVFEGAC--ICGVIYSFAMSLFLELRIINFVNLGLLALGPL 222
            ...|..|.:..|..|      .|.|.....|  |.|:...|...|.....::......|:.|..|
Frog   143 HAQYIGESAPRKLLGFLNCLAPMFVTLGKLCGQIVGIRELFGTELMWPYILVPSGITSLVQLITL 207

  Fly   223 QILMPESPAYYVD-HGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKK 286
            . |.||:|.|.:. .|:......:|:.|.|.: |.:.||:.:.......::....|.|...|...
Frog   208 P-LFPETPHYLLQVKGDKEACVKALKQLWGDR-DHQAEIEEMIEQQRAQKKTGNMGILELLKDPS 270

  Fly   287 VRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGL----ILGFLACFFLVDR 347
            .|..|...:.:.|..:|.||....||..::........:....:.:|:    .:..:.|..|::.
Frog   271 HRWQLYSMIGLILTMQLSGANAIYFYSYDVFRAANFPPDKISYVSIGVGAFEFVSAMVCSLLIEH 335

  Fly   348 LGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMS---WIALFCIAI---FVGCYTAGVGSLT 406
            .||:.|::   .|...:|:.|||     :|:.|::..   |:....:|:   |:..:.||.....
Frog   336 FGRKFLML---GGFSLMSLILGL-----LTVTLSLQDSYLWMPYCSVALVFSFIFVFGAGPAGSI 392

  Fly   407 WVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYL--------FLLFAIIASLI 463
            :....|:..:..|....::...|:|:..:.:...|        |||        ||||..:..:.
Frog   393 FTTCVEIFAQAPRVPALAVSGVFSWVGLYILGMIF--------PYLVGTLGHFCFLLFIAVMLIS 449

  Fly   464 LLFSLIYIPETKKLSSAKIQQ 484
            ...:...:||||..|.|:|.|
Frog   450 STLAFFIVPETKGKSIAQISQ 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	99/464 (21%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	36/184 (20%)
slc2a11l2	NP_001339155.2	MFS	17..468	CDD:421695	98/468 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000