DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and slc2a11.2

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001339156.1	Gene:	slc2a11.2 / 100496725	XenbaseID:	XB-GENE-5857129	Length:	489	Species:	Xenopus tropicalis

Alignment Length:	480	Identity:	120/480 - (25%)
Similarity:	206/480 - (42%)	Gaps:	95/480 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 GSFFFGIAVGWSGTAERSVME------QHSYS--FQPTE--LQWSGVCILLTLGAALWCLPMGLM 115
            |:|.:|:.:....:....:.:      ||.|.  ..|.:  |.||.:..:.::|..:..|.:|.:
Frog    25 GTFQYGLHISLINSPAEYIQKFINDTWQHRYGSPLHPDKITLFWSFIVSVYSIGGLMGSLIVGYL 89

  Fly   116 VRLLGCRRTILIQLLPNFLG---WFLTVFARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEISTTK 177
            ....|.::|.|...:...||   ..|:..|:|..|:..|||..|:..|....:..:|..|.:..|
Frog    90 SVSFGRKKTQLYNNVFALLGAALMMLSPVAQSFEMIIVGRFLYGVNTGVSLNLHTMYIGECAPKK 154

  Fly   178 KRGAMGVVFEGACICGVIYSFAMSLFLEL-RIINFV-----NLGLLALGP-----------LQIL 225
            .||               .|..:|||:.| :::.||     .||..||.|           :|:|
Frog   155 LRG---------------ISVTVSLFIALGKLMGFVVGLREFLGSEALWPYLMSFSAVPALVQLL 204

  Fly   226 ----MPESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYK 285
                .||||.| .:|..|......:::.|.|.. |...|:|.:..:....|.|.|:|.:...|.:
Frog   205 TLPFFPESPRYLLIDKDNKEGCLKAMQQLWGAG-DHVAEMDDMLAEKNSLEGEQRKGVMDLLKKR 268

  Fly   286 KVRRSLARSLAIALLQKLCGAL------IFIFYGLNMLDCLRIRREFGL------ILCLGL---- 334
            .||..:   ::|.|   .|||:      :..||..::.      |..|:      .:.||:
Frog   269 CVRWQM---ISIVL---TCGAIQLTGINVVYFYAYDVF------RNAGIPDRQIPFISLGIGVTE 321

  Fly   335 ILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVM---SWIALF---CIAI 393
            .|..:.|.|::||:||:||| :.:.|::.:::.|       :|..|::.   ||:..|   .|.|
Frog   322 ALTTVLCGFVIDRMGRKPLL-WINYGVITLTLSL-------LTATLSLQDLHSWMPYFSSALIFI 378

  Fly   394 FVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFVICW-FGSHGVKCQPYLFLLFA 457
            |...:..|.|.::.|:..|:.|:..||....::...||| ..|::.| |.........:.|:.|.
Frog   379 FTLSFGLGPGGVSCVIPTEMFVQSYRPAAYMLIGILNWL-GMFILAWSFPFMEAALGAFCFVFFI 442

  Fly   458 IIASLILLFSLIYIPETKKLSSAKI 482
            |:...:.:||.:.:||||..|..:|
Frog   443 ILCICMGIFSFLILPETKNKSILEI 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	120/480 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	45/196 (23%)
slc2a11.2	NP_001339156.1	MFS	22..467	CDD:391944	119/478 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910