Protein Alignment Glut3 and slc2a12

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_031758281.1
• Gene: slc2a12 / 100487147
• XenbaseID: XB-GENE-1012136
• Length: 591
• Species: Xenopus tropicalis
• Alignment Length: 587
• Identity: 112/587 - (19%)
• Similarity: 212/587 - (36%)
• Gaps: 171/587 - (29%)

  Fly    39 RAPVRQKINNVGLYKATLYSNIGSFFFGIAVGWS-GTAERSVMEQHSYSFQPTELQWSGVCILLT 102
            |...||.....|.....|.|::.:...|:.||:. |....::::..|. .:.|..|...|...|.
 Frog    22 RTNPRQTGKREGCGAFILLSSVIAAVSGLLVGYELGIISGALLQLQSL-LELTCQQQEIVVSALL 85

  Fly   103 LGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFARSVPM-------LYAGRFFLGMCGG 160
            :||.:..|..|.::.|.|.|.||:...:       |.||:..:|:       |.|||..:|:...
 Frog    86 IGAFVASLVGGSLIDLYGRRITIIFTSI-------LLVFSNLLPVVIVSYGSLIAGRIVIGVSIS 143

  Fly   161 AHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINF----VNLG------ 215
            ...:...:|.||||...|||.:..:.|...:.|:::::         |.|:    |:.|
 Frog   144 LSAIATCVYIAEISPQHKRGMLVSLNELMIVVGILFAY---------ICNYLFASVSNGWKYMFG 199

  Fly   216 -LLALGPLQIL----MPESPAYYVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVR 275
             ::.|..||.:    :|:||.:.:..|....|...|:.||.            |.:.:|....::
 Frog   200 LIIPLAALQAIAMYFLPQSPRFLIMKGYDDAAGKVLQKLRA------------TTNISEELTAIK 252

  Fly   276 QGPLLGFKYK---------KVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIR-REFGLIL 330
            ......::|:         .:|..|...|.::...::.|....:||...:|..:..: .|...:.
 Frog   253 SSIKAEYQYRFLDLFCSRDNMRVRLLIGLTLSFFVQITGQPNILFYASTVLKSVGFQSTEAASLA 317

  Fly   331 CLGL----ILGFLACFFLVDRLGRRPLLIFSSA-------GIVFVSIYLGLHF------------ 372
            ..|:    ::..:.....||::|.:..|...||       .:..||:.|.::|
 Frog   318 STGIGVIKVVSTIPAIIFVDKIGSKTFLCIGSAVMAVSLVSVGLVSLQLDVNFNNICKVHTMQNH 382

  Fly   373 -----------------------------------------KVW--------MTMGLT------- 381
                                                     |.|        .::|:|
 Frog   383 SLQDSIIYGPLSLSKPNESLFEETSTLESTKASYLSPLNGTKSWHFTTQEVDSSIGVTPKETKIK 447

  Fly   382 --------VMSWIALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNW------- 431
                    .|.|:.|..:..||..::.|:|.:.|::.:|:....::....:|..:.||
 Frog   448 SQPDGIPEYMKWLCLASLLAFVAAFSIGLGPMAWLVQSEIFPAGIKGRAFAITSSMNWGMNLLIS 512

  Fly   432 ---LTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQRLGGLINRP 493
               ||...:|      |:   |::...:|:::...|:|.::::|.||.....:|...|.   ||.
 Frog   513 LTFLTLTEII------GL---PWMLFGYALMSIASLVFVIMFVPNTKGRPLEEISMELA---NRS 565

  Fly   494 AV 495
            .|
 Frog   566 YV 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	103/555 (19%)
slc2a12	XP_031758281.1	MFS_GLUT12_Class3	40..557	CDD:340993	102/554 (18%)