DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	XP_038967504.1	Gene:	Slc2a7 / 100362644	RGDID:	1583902	Length:	525	Species:	Rattus norvegicus

Alignment Length:	521	Identity:	131/521 - (25%)
Similarity:	218/521 - (41%)	Gaps:	103/521 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SRKSGTWFAKRPSEMPERHVER--APVRQKINNVGLYKATLYSNIGSFF---FGIAV-------- 69
            |.::||       .:|..|:|.  .|.        |...||.:..||.|   :.|||
  Rat     3 SPETGT-------PLPSPHMEARLQPT--------LVLTTLSAAFGSAFQYGYNIAVINTPHKVG 52

  Fly    70 ---GWSGTAE-------RSVMEQHSYSFQPTE---LQWSGVCILLTLGAALWCLPMGLMVRLLGC 121
               ||....:       .:..|:|. :|....   |.||....:..||..|..|.:|:||...|.
  Rat    53 TSSGWGPVFQVLKSFYNDTYFERHG-TFMDENTLLLLWSCTVSMFPLGGLLGSLVVGMMVNKWGR 116

  Fly   122 RRTILIQLLPNFLGWFLTVF-------------ARSVPMLYAGRFFLGMCGGAHCVVVPIYNAEI 173
            :||:||.          .||             ||:..::...|..:|:|.|.....:|:|..|:
  Rat   117 KRTLLIN----------NVFAITSAVLMGASKAARAFELIIFSRVMVGICAGIAYSTLPMYLGEL 171

  Fly   174 STTKKRGAMGVVFEGACICGVIYSFAMSLFLELRIINFVNLG-------LLAL----GPLQIL-- 225
            :....||.:|.:.|...|.||:    ::....|:.|    ||       ||||    ..:|:|
  Rat   172 APQNLRGTLGTMTEVFVIFGVL----LAQIFSLQTI----LGNATGWPILLALTGVPALIQLLSL 228

  Fly   226 --MPESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESEREVRQGPLLGFKYKKV 287
              .||||.| .::.|:......:||.|||..|:...|::.:..:....:.|.|...|..|.::.:
  Rat   229 PFFPESPRYTLIEKGDEETTRQALRRLRGHSYNVEAEMEEMRTEERTEKAEGRLSVLNLFTFRPL 293

  Fly   288 RRSLARSLAIALLQKLCGA--------LIFIFYGLNMLDCLRIRREFGLILCLGLILGFLACFFL 344
            |..|...:.:...|:|.|.        :|:...|::......:....|:|   .|::..::. |:
  Rat   294 RWQLISIVVLMAGQQLSGINAVNYYADIIYTSAGVDPTQSQYVTLGSGVI---NLVMTLVSA-FI 354

  Fly   345 VDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLTVMSWIALFCIAIFVGCYTAGVGSLTWVL 409
            ::||||| :|:.|..||. .|..|.|...:.:...:..:|::.:.|:..::..::.|...:..|:
  Rat   355 IERLGRR-ILLLSGYGIC-GSACLVLTVALLLQSTVPELSYLGIICVFSYIVGHSIGPSPVPSVV 417

  Fly   410 NAELLVRPMRPLGCSIVCAFNWLTAFFVICWFGSHGVKCQPYLFLLFAIIASLILLFSLIYIPET 474
            ..|::::..|....::..|.:|||.|.|...|.|..|....|.||:||.|..|...:..:.||||
  Rat   418 RTEIVLQSSRTAAFTVDGAVHWLTNFIVGLTFPSIQVAIGAYSFLIFAGICLLTAAYIYVVIPET 482

  Fly   475 K 475
            |
  Rat   483 K 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	121/477 (25%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	52/214 (24%)
Slc2a7	XP_038967504.1	MFS_GLUT_Class2	26..490	CDD:340990	123/483 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.930