DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Glut3 and slc2a7

DIOPT Version :9

Sequence 1:	NP_536732.1	Gene:	Glut3 / 42036	FlyBaseID:	FBgn0015230	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001120033.1	Gene:	slc2a7 / 100144999	XenbaseID:	XB-GENE-5811422	Length:	501	Species:	Xenopus tropicalis

Alignment Length:	498	Identity:	116/498 - (23%)
Similarity:	193/498 - (38%)	Gaps:	77/498 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ERHVERAPVRQKINNVGLYKATLYSNI-GSFFFGIAVGWSGTAERSVME---QHSYSFQPTELQ- 93
            ::...|.|:.:      |:.|.....| |:|.:|..|.......|.:.:   ...||...:.|:
Frog     9 KKQTSRPPISR------LFLAVCAVGIGGAFQYGYNVSIINAPTRQIQQFINNTWYSRHQSNLEE 67

  Fly    94 ------WSGVCILLTLGAALWCLPMGLMVRLLGCRRTILIQLLPNFLGWFLTVFA---RSVPMLY 149
                  ||.:..:.|||..|.....|.:...||.::|:|:..:...|..||...|   ....:|.
Frog    68 GWLTLIWSVIASVFTLGGLLGTHIGGHLADKLGRKKTLLMNNVLAILAAFLMGIAYPSGCFELLI 132

  Fly   150 AGRFFLGMCGGAHCVVVPIYNAEISTTKKRG----AMGVVFEGACICGVI------------YSF 198
            .||..:|:..|....|.|:|..||:....||    .|.:...|....|.:            :.|
Frog   133 VGRLIIGINAGIGLCVQPLYLGEIAPRHIRGLTTVGMNIFLTGGIFTGQLVGLRELFGGGDNWYF 197

  Fly   199 AMSLFLELRIINFVNLGLLALGPLQILMPESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREIDF 262
            .:.......||...:|.         ..||||.| .:::.:..:.:.:|:.|.|.:: .:.|:|.
Frog   198 LLPTCCIPAIIQLASLP---------WFPESPRYLLIENKDEYQCQKALKMLYGSEH-YQPEMDD 252

  Fly   263 LTRDPTESEREVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFY--------GLNMLDC 319
            :.::......|..:.....|..:.||..|...:...:.|:|.|.....||        |:...:.
Frog   253 ILKESCALNGEKPKTIFQLFSDRTVRWQLVIIILTNIGQQLSGINAIYFYAAYVFTKAGIPANNI 317

  Fly   320 LRIRREFGLILCLGLILGFLACFFLVDRLGRRPLLIFSSAGIVFVSIYLGLHFKVWMTMGLT--- 381
            ..:....||..||..    |.|..|:|..|||.|:|   .|...::.:..:     :|:.||
Frog   318 PYVTLGTGLCECLTA----LTCGLLIDIAGRRILII---GGYTLMAFWCTI-----LTLTLTFQD 370

  Fly   382 VMSWI---ALFCIAIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFV--ICWF 441
            |..||   ::..:..|:..:..|.|.:|..|.|||..:..|.....|..:..|:|.|.:  |..|
Frog   371 VYPWIPYLSMSAVFAFILSFGLGPGGVTNTLTAELFTQSSRSAAFRISGSVGWITFFTIGMIFPF 435

  Fly   442 GSHGVKCQPYLFLLFAIIASLILLFSLIYIPETKKLSSAKIQQ 484
            ..:|:  ..|.||.|.:...|...|....:||||..|..:|::
Frog   436 LVNGL--NQYCFLFFFVECLLTASFIFFIVPETKNKSFLEIKK 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	Sugar_tr	60..484	CDD:278511	112/470 (24%)
Glut3	NP_536732.1	MFS	63..>226	CDD:119392	41/191 (21%)
slc2a7	NP_001120033.1	MFS_GLUT_Class2	23..474	CDD:340990	112/474 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910