Protein Alignment Glut3 and slc2a5

DIOPT Version :10

• Sequence 1: NP_536732.1
• Gene: Glut3 / 42036
• FlyBaseID: FBgn0015230
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001352581.1
• Gene: slc2a5 / 100006415
• ZFINID: ZDB-GENE-060222-2
• Length: 511
• Species: Danio rerio
• Alignment Length: 508
• Identity: 124/508 - (24%)
• Similarity: 224/508 - (44%)
• Gaps: 56/508 - (11%)

  Fly    34 ERHVERAPVRQKINNVGLYKATLYSNIGSFF---FGIAVGWSGTAERSVMEQHSY--SFQPTE-- 91
            |.::::...:.|:..: |..|:|.:..||.|   :.:||..|...|.....:..|  .:.|..
Zfish     4 EVNMKKGERKGKVTLI-LAAASLVAGFGSSFQYGYNVAVVNSPAPEMQQFYRRIYVDRYGPMSDN 67

  Fly    92 ---LQWSGVCILLTLGAALWCLPMGLMVRLLGCRRTIL----IQLLPNFLGWFLTVFARSVPMLY 149
               |.||....:..||.....|.:..:|...|.:.|:|    ..::|..: ..::..|.|..::.
Zfish    68 LLTLLWSVTVSMYPLGGFFGSLMVAPLVNKFGRKGTLLFNNIFSIVPAIM-MGVSEVAGSFEIII 131

  Fly   150 AGRFFLGMCGGAHCVVVPIYNAEISTTKKRGAMGVVFEGACICGVIYS--FAMSLFLELRIINFV 212
            ..||.:|:|.|....|||:|..||:....|||:|:|.:.....|::.:  |.:...|..:....:
Zfish   132 VARFLVGICAGLSSNVVPMYLGEIAPKNYRGAVGIVPQLFITVGILVAQIFGIRSILGNKEGWPI 196

  Fly   213 NLGLLAL-GPLQILM----PESPAY-YVDHGNIPRAEDSLRFLRGQKYDTRREIDFLTRDPTESE 271
            .|||..: ..:::|:    ||||.| .:..|:...|...|:.|||.: |...|:..: |...:||
Zfish   197 MLGLTGIPAAIELLLLPFFPESPRYMLIQKGDEKTARKGLQRLRGCE-DVDEELCEM-RVEEQSE 259

  Fly   272 R-EVRQGPLLGFKYKKVRRSLARSLAIALLQKLCGALIFIFYGLNMLDCLRIRREFGLILCLGL- 334
            | |.|...|..|.::.:|..|...:.:.:.|:|.|.....:|..::.....:..:....:.:|.
Zfish   260 RAEGRLSLLNLFTFRSLRWQLLSVIFMNMGQQLSGVNAIYYYADSIYSSAGVSEDHVQYVTVGTG 324

  Fly   335 ---ILGFLACFFLVDRLGRRPLLI--FSSAGIVFVSIYLGLHFKVWMTMGLTVMSWI---ALFCI 391
               :...:...|:|::.||:.||:  |.......|.:.:.|:|:       |.:.||   ::.|:
Zfish   325 AVNVFMTITAVFIVEKSGRKLLLLIGFGICCAACVILTIALYFQ-------TTLDWIPYVSIVCV 382

  Fly   392 AIFVGCYTAGVGSLTWVLNAELLVRPMRPLGCSIVCAFNWLTAFFV--ICWFGSHGVKCQPYLFL 454
            .::|..:..|...:..|:..|:..:..||....:..:.:||:.|.|  :..|...|:  .||.|:
Zfish   383 IVYVIGHAIGPSPIPTVITTEMFRQSSRPPAFMVAGSVHWLSNFTVGLVFPFLERGL--GPYSFI 445

  Fly   455 LFAIIASLILLFSLIYIPETKK---LSSAKIQQRLGGLINRPAVITFTSSSDS 504
            :||.|....|::..|.|||||.   |.::|:      ...|..|.....:|||
Zfish   446 IFACICLATLIYIWIVIPETKNKTFLETSKL------FAQRNKVEIMAEASDS 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Glut3	NP_536732.1	MFS_GLUT6_8_Class3_like	52..478	CDD:340916	114/462 (25%)
slc2a5	NP_001352581.1	MFS_GLUT_Class2	23..472	CDD:340990	114/460 (25%)