DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and hoxb3

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001015971.1	Gene:	hoxb3 / 548725	XenbaseID:	XB-GENE-482576	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	83/248 - (33%)
Similarity:	107/248 - (43%)	Gaps:	57/248 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 ANGQNNPA--GGMPVRPSACTPDSRVGGYLDTSGGSPV-SHRG-------------GSAGGNVSV 189
            |:..:||.  ||.|.:..:.       ||.......|. ||..             |.:|..|..
Frog     4 ASYYDNPTLFGGYPYQAGSL-------GYEGPQQSFPTSSHMDNEFQRSSCSLQSLGHSGPLVKA 61

  Fly   190 SGGNG-----NAGGVQSGVGVAGAGTAWNANCTISGAA------AQTAAASSLHQASNHTFYPWM 243
            ...||     |....||......|..:.|.|.:.|.|:      |::.|:.|  .||...| |||
Frog    62 KNLNGSCMRPNLSSEQSQPLSPTANPSSNTNSSSSQASLSKPSPAKSQASGS--PASKQIF-PWM 123

  Fly   244 AIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTL 308
                  .|....||.:|......          :||..|...|.  |::. .:|.|..||..|.:
Frog   124 ------KESRQNSKQKSSPPAPA----------AESCGGDRSPP--GSSA-SKRARTAYTSAQLV 169

  Fly   309 ELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELN 361
            |||||||.|.||.|.||:|||:.|.|:||||||||||||||.||: |.:|.::
Frog   170 ELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKD-QKVKGMS 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	36/52 (69%)
hoxb3	NP_001015971.1	Homeobox	160..212	CDD:306543	36/51 (71%)
hoxb3	NP_001015971.1	DUF4074	325..384	CDD:315871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910