Protein Alignment Ubx and HOXD11

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 360
• Identity: 95/360 - (26%)
• Similarity: 122/360 - (33%)
• Gaps: 131/360 - (36%)

  Fly    43 FPLSLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKDIWNTG 107
            ||.|..::|    |:|...:.:..|..:..| ...|..|.|                       |
Human    45 FPYSSNLAP----HVQPVREVAFRDYGLERA-KWPYRGGGG-----------------------G 81

  Fly   108 GSNGGG--GGGGGGGGGGAGG------TGGAGNANGGNAANANGQNN---PAGGMP------VRP 155
            ||.|||  |||.|||||||||      ...|..|....|..|..|..   |||..|      ..|
Human    82 GSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAAAAEEAAMQRELLPPAGRRPDVLFKAPEP 146

  Fly   156 SACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNG-------------------------- 194
            ....|             .|.....|:|....|..|.||
Human   147 VCAAP-------------GPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAAPGPPFAGPQPPPP 198

  Fly   195 -----NAGGVQSGVGVAGAGTAWNANCT--ISGAAAQTAAASSLHQASNHTFYPWMAIAGECPED 252
                 ..|....|....|||....:.||  ..|:..:.||..|                |...|.
Human   199 PAPPQPEGAADKGDPRTGAGGGGGSPCTKATPGSEPKGAAEGS----------------GGDGEG 247

  Fly   253 PTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTN 317
            |.                  |:..:|..:.::.|.      ..|:.|..||:||..|||:||..|
Human   248 PP------------------GEAGAEKSSSAVAPQ------RSRKKRCPYTKYQIRELEREFFFN 288

  Fly   318 HYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKK 352
            .|:.:.:|::::..|.||:||:||||||||||.||
Human   289 VYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	29/55 (53%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:432284	47/180 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		18/130 (14%)
		Homeodomain	267..323	CDD:459649	29/55 (53%)