Protein Alignment Ubx and HOXD4

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 82/273 - (30%)
• Similarity: 104/273 - (38%)
• Gaps: 94/273 - (34%)

  Fly   115 GGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHR 179
            ||.|.|.|.|....|.|...||...:......|....|..|.|..|.:|  .|..:....|.|
Human    63 GGSGPGPGSALPARGHGQEPGGPGGHYAAPGEPCPAPPAPPPAPLPGAR--AYSQSDPKQPPS-- 123

  Fly   180 GGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTFYPWMA 244
                                         |||......:                     ||||
Human   124 -----------------------------GTALKQPAVV---------------------YPWM- 137

  Fly   245 IAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLE 309
                       .|:.                     ..|:.|::  |.|..:|.|..|||.|.||
Human   138 -----------KKVH---------------------VNSVNPNY--TGGEPKRSRTAYTRQQVLE 168

  Fly   310 LEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAA 374
            ||||||.|.|||||||||:||.|||:||||||||||||||.||:   .|..|.:.:.:.:..:::
Human   169 LEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKD---HKLPNTKGRSSSSSSSSS 230

  Fly   375 AAAAAAAVQGGHL 387
            .:::.|..|  ||
Human   231 CSSSVAPSQ--HL 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	43/55 (78%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		21/96 (22%)
		Antp-type hexapeptide	133..138		4/37 (11%)
		Homeodomain	155..211	CDD:459649	43/55 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		6/35 (17%)