Protein Alignment Ubx and HOXC12

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_776272.1
• Gene: HOXC12 / 3228
• HGNCID: 5124
• Length: 282
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 86/330 - (26%)
• Similarity: 125/330 - (37%)
• Gaps: 126/330 - (38%)

  Fly    40 YRGFPLSLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDGAGAYKQDCLNIKADAVNGYKDIW 104
            |.|.|:||      |....||.:.:..:            ||.|.|::.|
Human    68 YLGSPVSL------NPPFGRTCELARVE------------DGKGYYREPC--------------- 99

  Fly   105 NTGGSNGGGGG-----GGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRV 164
                :.|||||     .|...|.|.|                      |..:|:.||.  |.: :
Human   100 ----AEGGGGGLKREERGRDPGAGPG----------------------AALLPLEPSG--PPA-L 135

  Fly   165 GGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWN-ANCTISGAAAQTAAA 228
            |...|.:.|                 ||.|:.||        |||...: .:|    .:.::.::
Human   136 GFKYDYAAG-----------------GGGGDGGG--------GAGPPHDPPSC----QSLESDSS 171

  Fly   229 SSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNG 293
            |||....|         .|....||  ..:.|.|...||:|.          :|:   .|...|.
Human   172 SSLLNEGN---------KGAGAGDP--GSLVSPLNPGGGLSA----------SGA---PWYPINS 212

  Fly   294 LRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIK 358
            ..|:.|:.|::.|..|||.||..|.::||:||.|::..|.|:::|:||||||||||.|:.:
Human   213 RSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLL---- 273

  Fly   359 ELNEQ 363
             |.||
Human   274 -LREQ 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	28/55 (51%)
HOXC12	NP_776272.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..129		13/75 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..214		22/102 (22%)
		Homeodomain	215..271	CDD:459649	28/55 (51%)