Protein Alignment Ubx and HOXC8

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 79/221 - (35%)
• Similarity: 109/221 - (49%)
• Gaps: 60/221 - (27%)

  Fly   189 VSGGNGNAGGVQSG------------VGVAGAGTAWNANCTIS--GAAAQTAAASSLHQASNHTF 239
            |.|..|:|.|.|..            .|::.:|...|. |::|  |.|::              |
Human    39 VYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNP-CSLSCHGDASK--------------F 88

  Fly   240 YPWMAIAGECPEDPTKS----KIRSDLTQYGGISTDMGKRYSE-------SLAGSLLPDWLGTNG 293
            |.:.|:       |.:|    :..:.:.||....:......||       :.:.||:..|:..:.
Human    89 YGYEAL-------PRQSLYGAQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHA 146

  Fly   294 L-RRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAI 357
            . ||.|||||:|||||||||||..|.||||:||||::|||.|||||:||||||||||.|||....
Human   147 PGRRSGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKD 211

  Fly   358 K------------ELNEQEKQAQAQK 371
            |            |.||:|::.:.:|
Human   212 KLPGARDEEKVEEEGNEEEEKEEEEK 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	44/55 (80%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		8/39 (21%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeodomain	150..206	CDD:459649	44/55 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		8/32 (25%)