Protein Alignment Ubx and HOXB8

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 91/277 - (32%)
• Similarity: 115/277 - (41%)
• Gaps: 94/277 - (33%)

  Fly   150 GMPVRPS--ACTPDSRVGGYLDTSGGSPVSHRGGSAGGN-------------------------- 186
            |..:||:  .|       |:....||.|....|.|:||:
Human    16 GESLRPNYYDC-------GFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNP 73

  Fly   187 --VSVSGGNGNAGGV-----QSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHT-FYPWM 243
              |:..|..||..|.     ||..|.........|:|.::.|:.....|....|:.:.| .:|||
Human    74 CAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWM 138

  Fly   244 AIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTL 308
            .                                .::.||            ||||||||:|||||
Human   139 R--------------------------------PQAAAG------------RRRGRQTYSRYQTL 159

  Fly   309 ELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIK------ELNEQEKQA 367
            ||||||..|.||||:||||::|||.|||||:||||||||||.|||....|      |..|.|||
Human   160 ELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQ- 223

  Fly   368 QAQKAAAAAAAAAAVQG 384
            :.::|..||....|.:|
Human   224 KLERAPEAADEGDAQKG 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	45/55 (82%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		2/4 (50%)
		Homeodomain	147..203	CDD:459649	45/55 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		13/39 (33%)