DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubx and HOXB7

DIOPT Version :9

Sequence 1:NP_536752.1 Gene:Ubx / 42034 FlyBaseID:FBgn0003944 Length:389 Species:Drosophila melanogaster
Sequence 2:NP_004493.3 Gene:HOXB7 / 3217 HGNCID:5118 Length:217 Species:Homo sapiens


Alignment Length:215 Identity:86/215 - (40%)
Similarity:106/215 - (49%) Gaps:68/215 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 GGSAGGNVSVS------GGNGNAGGVQSGVGVAGAG---TAWNANC-----TISGA----AAQTA 226
            |..:|.:.:.|      ||.|.||...:||..||.|   :::|.:|     .:||.    :|:.|
Human    44 GAGSGASFAASMQGLYPGGGGMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAA 108

  Fly   227 AA-----SSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLP 286
            .|     |.|...||...||||..:|                      ||               
Human   109 GAKEQRDSDLAAESNFRIYPWMRSSG----------------------TD--------------- 136

  Fly   287 DWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLK 351
                    |:|||||||||||||||||||.|.|||||||||:||.||||||||||||||||||.|
Human   137 --------RKRGRQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWK 193

  Fly   352 KEIQAIKELNEQEKQAQAQK 371
            ||.:........:.:|:|::
Human   194 KENKTAGPGTTGQDRAEAEE 213

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UbxNP_536752.1 Homeobox 299..352 CDD:395001 47/52 (90%)
HOXB7NP_004493.3 Antp-type hexapeptide 126..131 3/4 (75%)
Homeobox 141..193 CDD:278475 47/51 (92%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 194..217 4/20 (20%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000007
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45659
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.910

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