Protein Alignment Ubx and HOXB5

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 105/325 - (32%)
• Similarity: 135/325 - (41%)
• Gaps: 100/325 - (30%)

  Fly    97 VNGYKDIWNTGGS----NGGGGGGGGGG--GGGAGGTGGAG-NANG-------GNAANAN----G 143
            ||.:...:..|..    |.|.|....|.  ...|..||..| |.||       .:|::::    |
Human     6 VNSFSGRYPNGPDYQLLNYGSGSSLSGSYRDPAAMHTGSYGYNYNGMDLSVNRSSASSSHFGAVG 70

  Fly   144 QNNPAGGMPVR-------PSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQS 201
            :::.|...|.:       .|:|:        |.:....|.:: |.|.|...|.|..:..|....|
Human    71 ESSRAFPAPAQEPRFRQAASSCS--------LSSPESLPCTN-GDSHGAKPSASSPSDQATSASS 126

  Fly   202 GVGVAGAGTAWNANCT-ISGAAAQT---AAASSLHQASNHTFYPW-MAIAGECPEDPT------- 254
                       :||.| |..|:|.:   .|||.|...|.....|. ||.:...||..|
Human   127 -----------SANFTEIDEASASSEPEEAASQLSSPSLARAQPEPMATSTAAPEGQTPQIFPWM 180

  Fly   255 -KSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNH 318
             |..|..|:|                          |.:|  :|.|..||||||||||||||.|.
Human   181 RKLHISHDMT--------------------------GPDG--KRARTAYTRYQTLELEKEFHFNR 217

  Fly   319 YLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAVQ 383
            |||||||||:||||||:||||||||||||||.||:              ...|:.:.|.|.:|.|
Human   218 YLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKD--------------NKLKSMSLATAGSAFQ 268

  Fly   384  383
            Human   269  268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	46/55 (84%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	29/123 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		28/115 (24%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	195..251	CDD:459649	46/55 (84%)