Protein Alignment Ubx and HOXB1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_002135.2
• Gene: HOXB1 / 3211
• HGNCID: 5111
• Length: 301
• Species: Homo sapiens
• Alignment Length: 310
• Identity: 92/310 - (29%)
• Similarity: 114/310 - (36%)
• Gaps: 95/310 - (30%)

  Fly    74 CNKIYGDGAGAYKQDCLNI-----KADAVNGYKDIWNTGGSNGGGGGGGGGGGGGAGGTGGAGNA 133
            ||:    |..||.......     .|.||:.|       .|.|..||         |.:..|...
Human    15 CNR----GPSAYSAHSAPTSFPPSSAQAVDSY-------ASEGRYGG---------GLSSPAFQQ 59

  Fly   134 NGGNAANANGQNNPAG-GMP--------VRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSV 189
            |.|..|    |..|:. |:|        ..|:||:|......|.      |:....|. ||....
Human    60 NSGYPA----QQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYY------PLGQSEGD-GGYFHP 113

  Fly   190 SGGNGNAGGVQSGVGVAGAGTA--------WNANCTISGAAA---------QTAAASSLHQASNH 237
            |......||:..|.|..|||..        :....|.|.|.|         :|...|..:..:..
Human   114 SSYGAQLGGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTAR 178

  Fly   238 TFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTY 302
            || .||.:    ..:|.|:                 .:.||...||  |..|.||         :
Human   179 TF-DWMKV----KRNPPKT-----------------AKVSEPGLGS--PSGLRTN---------F 210

  Fly   303 TRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKK 352
            |..|..|||||||.|.||:|.||:|:|..|.|.|.|:||||||||||.||
Human   211 TTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKK 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	31/55 (56%)
HOXB1	NP_002135.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..77		19/76 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	127..149		4/21 (19%)
		Antp-type hexapeptide	179..184		3/5 (60%)
		Homeodomain	207..260	CDD:459649	33/61 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	254..301		6/7 (86%)