DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and hoxa2b

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_571181.1	Gene:	hoxa2b / 30325	ZFINID:	ZDB-GENE-990415-98	Length:	363	Species:	Danio rerio

Alignment Length:	160	Identity:	57/160 - (35%)
Similarity:	75/160 - (46%)	Gaps:	24/160 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 NANCTISGAAAQTAAASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYS 277
            |.:|.:..|:....             ||||         ..|...:.:.|.....:||.|..|.
Zfish    75 NGSCPLPAASLPPE-------------YPWM---------KEKKASKKNQTTSTAATTDPGPLYF 117

  Fly   278 ESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIW 342
            .......:.|  |.:|..||.|..||..|.||||||||.|.||.|.||:|:|..|.|||||:|:|
Zfish   118 SPQGSPEISD--GGSGATRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVW 180

  Fly   343 FQNRRMKLKKEIQAIKELNEQEKQAQAQKA 372
            |||||||.|::.|..:..:...|....::|
Zfish   181 FQNRRMKHKRQTQCKENHHGDGKPPSLEEA 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	35/52 (67%)
hoxa2b	NP_571181.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..132		15/80 (19%)
		Antp-type hexapeptide	88..93		4/26 (15%)
		Homeobox	137..189	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..218		6/25 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	245..279
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810