Protein Alignment Ubx and TLX3

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 61/246 - (24%)
• Similarity: 98/246 - (39%)
• Gaps: 59/246 - (23%)

  Fly   152 PVRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVS--------GGNG----NAGGVQSGVG 204
            |.:.||..|          .|....|:.||..||....:        .|.|    :||.....:.
Human    27 PDQDSAPAP----------RGPDGASYLGGPPGGRPGATYPSLPASFAGLGAPFEDAGSYSVNLS 81

  Fly   205 VAGAGT-AWNANCTISGAA-----------AQTAAASSLHQASNHTFYPWMAIAGECPEDPTKSK 257
            :|.||. ...|:..:.||.           ......|||...:    :|||..:....:|  :..
Human    82 LAPAGVIRVPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN----FPWMESSRRFVKD--RFT 140

  Fly   258 IRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTR 322
            ..:.||.: .::..:|..|...           |...|::.|.:::|.|..||||.||...||..
Human   141 AAAALTPF-TVTRRIGHPYQNR-----------TPPKRKKPRTSFSRVQICELEKRFHRQKYLAS 193

  Fly   323 RRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAA 373
            ..|..:|.:|.:|:.|:|.||||||.|.:::       ..:|::|:.|:|:
Human   194 AERAALAKSLKMTDAQVKTWFQNRRTKWRRQ-------TAEEREAERQQAS 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	24/55 (44%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		10/38 (26%)
		Homeodomain	167..223	CDD:459649	24/55 (44%)