DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubx and Hoxd3

DIOPT Version :9

Sequence 1:	NP_536752.1	Gene:	Ubx / 42034	FlyBaseID:	FBgn0003944	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001257967.1	Gene:	Hoxd3 / 288152	RGDID:	1588601	Length:	432	Species:	Rattus norvegicus

Alignment Length:	392	Identity:	104/392 - (26%)
Similarity:	135/392 - (34%)	Gaps:	134/392 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QASGFYGHPHQATGMAMGSGGHHDQTASAAAAAYRGFPLSLGMSPYANHHLQRTTQDSPYDASIT 71
            |.:.:|.:|    |:..|.|      .|.|..|| |:                :|...||..  .
  Rat    18 QKAAYYENP----GLFGGYG------YSKATDAY-GY----------------STPHQPYPP--P 53

  Fly    72 AACNKIYGDGAGAYKQDCLNIKADA-----------VNGYKDIWNTGGSNGGGGGGGGGGGGGAG 125
            ||.|.:..|    |.....:|::.|           :||......||.|.|||||....|
  Rat    54 AAANSLDSD----YPSSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGNQPPG----- 109

  Fly   126 GTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVS 190
                           .|.:..|.  .|..|....|.|.     .|:.||.|..:....|.|.|
  Rat   110 ---------------LNSEQQPP--QPPPPPPTLPPSS-----PTNPGSGVPAKKTKGGPNAS-- 150

  Fly   191 GGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTFYPWMAIAGECPEDPTK 255
                                  :::.|||                 ...:|||      .|....
  Rat   151 ----------------------SSSSTIS-----------------KQIFPWM------KESRQN 170

  Fly   256 SKIRSDLTQYGGISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYL 320
            ||                ::.|.:.:|....|........:|.|..||..|.:|||||||.|.||
  Rat   171 SK----------------QKNSCATSGENCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYL 219

  Fly   321 TRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAVQGG 385
            .|.||:|||:.|.||||||||||||||||.||:.:|...|:....|:..:......||......|
  Rat   220 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPAGQSPERSPPLGGAAGHVAYSG 284

  Fly   386 HL 387
            .|
  Rat   285 QL 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	37/52 (71%)
Hoxd3	NP_001257967.1	Homeobox	198..251	CDD:395001	37/52 (71%)
Hoxd3	NP_001257967.1	DUF4074	369..430	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810