Protein Alignment Ubx and Tlx3

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_036012630.1
• Gene: Tlx3 / 27140
• MGIID: 1351209
• Length: 338
• Species: Mus musculus
• Alignment Length: 286
• Identity: 71/286 - (24%)
• Similarity: 111/286 - (38%)
• Gaps: 76/286 - (26%)

  Fly   134 NGGNAANANGQNNPAGGMPVRP-------SACTPDSR--VGGYLDTSGGSP-------------V 176
            ||..||:.     |:...|.||       ||.||...  :...:|....||             .
Mouse    29 NGDPAASP-----PSPAQPFRPPRMEAPASAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGA 88

  Fly   177 SHRGGSAGGNVSVS--------GGNG----NAGGVQSGVGVAGAGT-AWNANCTISGAA------ 222
            |:.||..||....:        .|.|    :||.....:.:|.||. ...|:..:.||.
Mouse    89 SYLGGPPGGRPGAAYPSLPASFAGLGAPFEDAGSYSVNLSLAPAGVIRVPAHRPLPGAVPPPLPS 153

  Fly   223 -----AQTAAASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAG 282
                 ......|||...:    :|||..:....:|  :....:.||.: .::..:|..|...
Mouse   154 ALPAMPSVPTVSSLGGLN----FPWMESSRRFVKD--RFTAAAALTPF-TVTRRIGHPYQNR--- 208

  Fly   283 SLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRR 347
                    |...|::.|.:::|.|..||||.||...||....|..:|.:|.:|:.|:|.||||||
Mouse   209 --------TPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRR 265

  Fly   348 MKLKKEIQAIKELNEQEKQAQAQKAA 373
            .|.:::       ..:|::|:.|:|:
Mouse   266 TKWRRQ-------TAEEREAERQQAS 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	24/55 (44%)
Tlx3	XP_036012630.1	PRK07764	<20..>109	CDD:236090	20/84 (24%)
		Homeodomain	214..270	CDD:459649	24/55 (44%)