Protein Alignment Ubx and GBX1

DIOPT Version :9

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001092304.1
• Gene: GBX1 / 2636
• HGNCID: 4185
• Length: 363
• Species: Homo sapiens
• Alignment Length: 351
• Identity: 94/351 - (26%)
• Similarity: 124/351 - (35%)
• Gaps: 118/351 - (33%)

  Fly   111 GGGGGGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGG----------MPVRPSACTPDSRVG 165
            |||...||.||||.||.|.|.:.:     :..|...|..|          ||.|| ...|.:...
Human     5 GGGSAPGGNGGGGGGGPGTAFSID-----SLIGPPPPRSGHLLYTGYPMFMPYRP-LVLPQALAP 63

  Fly   166 GYLDTSGGSPVSHRGGSAGGNVSV-SGGNGNAGGVQSGVGVAGA-------GTAWNANCTISGAA 222
            ..| .:|..|::.....||...:. ..|.|.|  |.|.|.:..|       ..|:.....::.||
Human    64 APL-PAGLPPLAPLASFAGRLTNTFCAGLGQA--VPSMVALTTALPSFAEPPDAFYGPQELAAAA 125

  Fly   223 AQTAAASSLHQAS---------------------------------NHTFYPWMAIAGECPEDPT 254
            |..||.::.:...                                 :.||          |..|.
Human   126 AAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETF----------PSLPA 180

  Fly   255 KSKIRSDLTQ------------------YGGISTDMGKRYSESLAGS---------LLPDWLGT- 291
            :.|:.|...:                  .||.|.|.|  :.:|.||.         .|...|||
Human   181 EGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDG--FLDSSAGGPGALLGPKPKLKGSLGTG 243

  Fly   292 --------------NGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIW 342
                          .|..||.|..:|..|.||||||||...||:...|.::||||.|:|.|:|||
Human   244 AEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIW 308

  Fly   343 FQNRRMKLKKEIQAIKELNEQEKQAQ 368
            |||||.|.|:    ||..|...:..:
Human   309 FQNRRAKWKR----IKAGNVSSRSGE 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeobox	299..352	CDD:395001	30/52 (58%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31		13/30 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	128..265		23/148 (16%)
		Homeobox	264..317	CDD:306543	30/52 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810