Protein Alignment Ubx and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 266
• Identity: 73/266 - (27%)
• Similarity: 110/266 - (41%)
• Gaps: 61/266 - (22%)

  Fly   151 MPVRPSACTPDS-------------RVGGYLDTSG---GSPVSHRGGSAGGNVSVSGGNGNAGGV 199
            |.:.|...||.|             :.||.:|.:.   |:|:    |:|......||.:..|..|
Mouse     1 MSLSPKHTTPFSVSDILSPIEETYKKFGGVMDGAPPGLGAPL----GAAAYRAPPSGPSSQAAAV 61

  Fly   200 QSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTFYPWMAIA----------GECP--ED 252
            .:|:....|....||....:.|||..|||::.|.....:.:|..|:.          ||.|  .|
Mouse    62 AAGMQPPHAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQFPHSAMGSYCNGGLGNMGELPAYTD 126

  Fly   253 PTKSKIRSDLTQYGGISTDMGKRYSE-----------------SLAG------SLLPDWLGTNGL 294
            ..:....:..|.:.|.:||  .|||.                 ||.|      ||.|  |.....
Mouse   127 GMRGGAAAAATGWYGANTD--PRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLAP--LHAAAP 187

  Fly   295 RRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEI--QAI 357
            ||:.|..:::.|..|||:.|....||:...|..:|..:.||..|:||||||.|.|:|::.  :|.
Mouse   188 RRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAA 252

  Fly   358 KELNEQ 363
            ::|.::
Mouse   253 QQLQQE 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	22/55 (40%)
Nkx2-4	NP_075993.1	Homeodomain	189..245	CDD:459649	22/55 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		2/14 (14%)