Protein Alignment Ubx and Tlx1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: XP_006526978.1
• Gene: Tlx1 / 21908
• MGIID: 98769
• Length: 345
• Species: Mus musculus
• Alignment Length: 366
• Identity: 99/366 - (27%)
• Similarity: 140/366 - (38%)
• Gaps: 103/366 - (28%)

  Fly    26 GGHHDQTASAAAAAYRGFPLSLGMSPYANHHLQRTTQDSPYDASITAACNKIYGDGAGAYKQDCL 90
            |.||.....|.       |:|.|:....|         ||.........:::..   |.|...||
Mouse     5 GPHHLHPGHAE-------PISFGIDQILN---------SPDQGGCMGPASRLQD---GDYGLGCL 50

  Fly    91 NIKADAVNGYKDIWNTGGSNGGGGGGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRP 155
                           .||:. ..||||...|.||||||..|      |....|...||||
Mouse    51 ---------------VGGAY-TYGGGGSAAGAGAGGTGAYG------AGGPGGPGGPAGG----- 88

  Fly   156 SACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNG-NAGGVQSGVGVAGAGTAWN-----A 214
                     ||...:.|..|     ||...|::::||.| ..||...|.|.|||.:|..     |
Mouse    89 ---------GGGACSMGPLP-----GSYNVNMALAGGPGPGGGGGGGGAGGAGALSAAGVIRVPA 139

  Fly   215 NCTISGAAA-------------QTAAASSLHQASNHTFYPWMAIAGECPEDPTKSKIRSDLTQYG 266
            :..::||.|             ...|...::..:..|| |||    |.....||.:....|:.:
Mouse   140 HRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTF-PWM----ESNRRYTKDRFTVALSPF- 198

  Fly   267 GISTDMGKRYSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHA 331
            .::..:|..|...           |...:::.|.::||.|..||||.||...||....|..:|.|
Mouse   199 TVTRRIGHPYQNR-----------TPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKA 252

  Fly   332 LCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKA 372
            |.:|:.|:|.||||||.|.:::       ..:|::|:.|:|
Mouse   253 LKMTDAQVKTWFQNRRTKWRRQ-------TAEEREAERQQA 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	26/55 (47%)
Tlx1	XP_006526978.1	Homeodomain	217..273	CDD:459649	26/55 (47%)