Protein Alignment Ubx and EMX2

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_004089.1
• Gene: EMX2 / 2018
• HGNCID: 3341
• Length: 252
• Species: Homo sapiens
• Alignment Length: 251
• Identity: 62/251 - (24%)
• Similarity: 95/251 - (37%)
• Gaps: 86/251 - (34%)

  Fly   152 PVRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANC 216
            |:||:|          |..:..||:         |..::|.:..|      ...||.|...|.:.
Human    30 PIRPAA----------LSYANSSPI---------NPFLNGFHSAA------AAAAGRGVYSNPDL 69

  Fly   217 TISGAAA---------------QTAAASSL------------HQASNHTFYPWMAIAGECPEDPT 254
            ..:.|.:               ...||..|            .|....|||||:
Human    70 VFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWL----------- 123

  Fly   255 KSKIRSDLTQYGGISTDMGKRYSESLAGSLLPD-WLGTNGLRRRGRQTYTRY---QTLELEKEFH 315
                   :.:|    ..:|.|:.   .....|: :|..|.|.|:.::..|.:   |.|.||..|.
Human   124 -------IHRY----RYLGHRFQ---GNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFE 174

  Fly   316 TNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQK 371
            .|||:....|.::||:|.|||.|:|:||||||.|.|::     :|.|:...:|.:|
Human   175 KNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQ-----KLEEEGSDSQQKK 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	26/58 (45%)
EMX2	NP_004089.1	Homeodomain	155..211	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..252		4/19 (21%)