Protein Alignment Ubx and EMX1

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 70/286 - (24%)
• Similarity: 107/286 - (37%)
• Gaps: 98/286 - (34%)

  Fly   110 NGGGGGGGGGGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPSACTPDSRVGGYLDTSGGS 174
            :||.|||.||||.|:.....|                 |...|:||:|
Human    52 DGGTGGGTGGGGAGSHLLAAA-----------------ASEEPLRPTA----------------- 82

  Fly   175 PVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAGTAWNANCTISGAAAQTAAASSLHQA----- 234
             :::...||.....|||....|        .||||.:......:....|....|.::|.|
Human    83 -LNYPHPSAAEAAFVSGFPAAA--------AAGAGRSLYGGPELVFPEAMNHPALTVHPAHQLGA 138

  Fly   235 -----------SNHT----FYPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSESLAGSL 284
                       :.|.    ||||:              :|:..         .|.|:.   |..:
Human   139 SPLQPPHSFFGAQHRDPLHFYPWV--------------LRNRF---------FGHRFQ---ASDV 177

  Fly   285 LPDWLGTNG----LRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQN 345
            ..|.|..:|    ..:|.|..::..|.|.||:.|..|||:....|.::|.:|.|:|.|:|:||||
Human   178 PQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQN 242

  Fly   346 RRMKLKKEIQAIKELNEQEKQAQAQK 371
            ||.|.|::     :|.|:..:::.:|
Human   243 RRTKYKRQ-----KLEEEGPESEQKK 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	24/55 (44%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		3/20 (15%)