DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubx and Pdx1

DIOPT Version :9

Sequence 1:NP_536752.1 Gene:Ubx / 42034 FlyBaseID:FBgn0003944 Length:389 Species:Drosophila melanogaster
Sequence 2:NP_032840.1 Gene:Pdx1 / 18609 MGIID:102851 Length:284 Species:Mus musculus


Alignment Length:166 Identity:58/166 - (34%)
Similarity:73/166 - (43%) Gaps:48/166 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   225 TAAASSLHQASNHTFYPWMAIAGECP----EDPTKSKIRSDL-----------------TQYGGI 268
            |::..||.|.|.....|:     |.|    :||..:.:...|                 |:.||:
Mouse    51 TSSLGSLEQGSPPDISPY-----EVPPLASDDPAGAHLHHHLPAQLGLAHPPPGPFPNGTEPGGL 110

  Fly   269 STD---------MGKRYSESLAGSLLPDWLGTNGL-------RRRGRQTYTRYQTLELEKEFHTN 317
            ...         |....:.:..|    .|.|  |.       .:|.|..|||.|.|||||||..|
Mouse   111 EEPNRVQLPFPWMKSTKAHAWKG----QWAG--GAYTAEPEENKRTRTAYTRAQLLELEKEFLFN 169

  Fly   318 HYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKKE 353
            .|::|.||:|:|..|.||||.|||||||||||.|||
Mouse   170 KYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKE 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UbxNP_536752.1 Homeobox 299..352 CDD:395001 35/52 (67%)
Pdx1NP_032840.1 Transactivation domain. /evidence=ECO:0000250 13..73 8/26 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 30..116 14/69 (20%)
Antp-type hexapeptide 119..124 0/4 (0%)
Homeobox 150..203 CDD:278475 35/52 (67%)
Nuclear localization signal 198..204 4/5 (80%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 202..284 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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