DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ubx and DLX5

DIOPT Version :10

Sequence 1:NP_536752.1 Gene:Ubx / 42034 FlyBaseID:FBgn0003944 Length:389 Species:Drosophila melanogaster
Sequence 2:NP_005212.1 Gene:DLX5 / 1749 HGNCID:2918 Length:289 Species:Homo sapiens


Alignment Length:245 Identity:57/245 - (23%)
Similarity:90/245 - (36%) Gaps:56/245 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   145 NNPAGGMPVRPSACTPDSRVGGYLDTSGGSPVSHRGGSAGGNVSVSGGNGNAGGVQSGVGVAGAG 209
            ::|:...|..|.:...||   .|...:||:|                                  
Human    28 HHPSQESPTLPESSATDS---DYYSPTGGAP---------------------------------- 55

  Fly   210 TAWNANCTISGAAAQTAAASSLHQASNHTFYPWMAIAGECPEDPTKS----KIRSDLTQYGGIST 270
                     .|..:.|:|  |..:|.|...|.:..:.|.....|.|:    ...|...||||...
Human    56 ---------HGYCSPTSA--SYGKALNPYQYQYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYN 109

  Fly   271 DMGKRYSESLAGSLLPDWLGTNGLR---RRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHAL 332
            .:....::.......|:....||..   |:.|..|:.:|...|::.|....||....|.|:|.:|
Human   110 RVPSATNQPEKEVTEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASL 174

  Fly   333 CLTERQIKIWFQNRRMKLKKEIQAIKELNEQEKQAQAQKAAAAAAAAAAV 382
            .||:.|:||||||:|.|:|| |....|:..:...:.:...|..:..:.||
Human   175 GLTQTQVKIWFQNKRSKIKK-IMKNGEMPPEHSPSSSDPMACNSPQSPAV 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UbxNP_536752.1 Homeodomain 296..352 CDD:459649 23/55 (42%)
DLX5NP_005212.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..49 6/23 (26%)
DLL_N 32..118 CDD:463567 23/133 (17%)
Homeodomain 138..194 CDD:459649 23/55 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 198..251 4/26 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 270..289
Blue background indicates that the domain is not in the aligned region.

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