Protein Alignment Ubx and NKX2-5

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_004378.1
• Gene: NKX2-5 / 1482
• HGNCID: 2488
• Length: 324
• Species: Homo sapiens
• Alignment Length: 145
• Identity: 40/145 - (27%)
• Similarity: 59/145 - (40%)
• Gaps: 29/145 - (20%)

  Fly   220 GAAAQTAAASSLHQASNHTFYPWMAIAGECPEDPTKSK---------IRSDLTQYGGISTDMGKR 275
            |.|...|..:|...|: ..|||......:..:||...|         :..:.|:.........:|
Human    74 GRAPSPAKCASAFPAA-PAFYPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARR 137

  Fly   276 YSESLAGSLLPDWLGTNGLRRRGRQTYTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIK 340
                               ||:.|..:::.|..|||:.|....||:...|.::|..|.||..|:|
Human   138 -------------------RRKPRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVK 183

  Fly   341 IWFQNRRMKLKKEIQ 355
            |||||||.|.|::.|
Human   184 IWFQNRRYKCKRQRQ 198

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	24/55 (44%)
NKX2-5	NP_004378.1	Homeodomain	145..195	CDD:459649	22/49 (45%)