Protein Alignment Ubx and En2

DIOPT Version :10

• Sequence 1: NP_536752.1
• Gene: Ubx / 42034
• FlyBaseID: FBgn0003944
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_034264.1
• Gene: En2 / 13799
• MGIID: 95390
• Length: 324
• Species: Mus musculus
• Alignment Length: 311
• Identity: 89/311 - (28%)
• Similarity: 111/311 - (35%)
• Gaps: 107/311 - (34%)

  Fly   109 SNGGGGGGG-------------------------------------------------------G 118
            |:|||.|||                                                       .
Mouse    22 SSGGGSGGGSSPSDSDTGRRRALMLPEVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCA 86

  Fly   119 GGGGGAGGTGGAGNANGGNAANANGQNNPAGGMPVRPS-ACTPDSRVGGYLDTSGGSP-VSHRGG 181
            |.||..||.||||...|| ...|.|.....|....||: ||.|.:  ||.|..:.|.| |...||
Mouse    87 GAGGARGGEGGAGTTEGG-GGGAGGAEQLLGARESRPNPACAPSA--GGTLSAAAGDPAVDGEGG 148

  Fly   182 SAGGNVSVSGG---NGNAGGVQSGV----GVAGAGTAWNANCTISGAAAQTAAASSLHQASNHTF 239
            |.  .:|:.||   .|:.||...||    |:.|...:.:::...|.|:|...|...|..|
Mouse   149 SK--TLSLHGGAKKPGDPGGSLDGVLKARGLGGGDLSVSSDSDSSQASATLGAQPMLWPA----- 206

  Fly   240 YPWMAIAGECPEDPTKSKIRSDLTQYGGISTDMGKRYSE---SLAGSLLPDWLGTNGLRRRGRQT 301
              |:...                            |||:   |...|..|.....|...:|.|..
Mouse   207 --WVYCT----------------------------RYSDRPSSGPRSRKPKKKNPNKEDKRPRTA 241

  Fly   302 YTRYQTLELEKEFHTNHYLTRRRRIEMAHALCLTERQIKIWFQNRRMKLKK 352
            :|..|...|:.||.||.|||.:||..:|..|.|.|.||||||||:|.|:||
Mouse   242 FTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubx	NP_536752.1	Homeodomain	296..352	CDD:459649	28/55 (51%)
En2	NP_034264.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..59		7/36 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..174		35/89 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..240		5/24 (21%)
		Homeodomain	236..292	CDD:459649	28/55 (51%)
		Engrail_1_C_sig	293..323	CDD:431338	89/311 (29%)